Showing entry for Isocitrate dehydrogenase [NADP], mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011029
Protein NameIsocitrate dehydrogenase [NADP], mitochondrial
Uniport IdP54071
GeneIdh2
Gene Id269951
DomainIso_dh
Pfam PF00180  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006103 2-oxoglutarate metabolic process
Biological Process GO:0006097 glyoxylate cycle
Biological Process GO:0006102 isocitrate metabolic process
Biological Process GO:0006741 NADP biosynthetic process
Biological Process GO:0006739 NADP metabolic process
Biological Process GO:1903976 negative regulation of glial cell migration
Biological Process GO:0060253 negative regulation of glial cell proliferation
Biological Process GO:1904465 negative regulation of matrix metallopeptidase secretion
Biological Process GO:0006099 tricarboxylic acid cycle
molecular function GO:0004450 isocitrate dehydrogenase (NADP+) activity
molecular function GO:0004448 isocitrate dehydrogenase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0051287 NAD binding
cellular component GO:0005829 cytosol
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005777 peroxisome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0006342 (1R,2S)-Isocitric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein