protein

General Target Information
BXGT Id	BXGT011060
Protein Name	5'-AMP-activated protein kinase subunit gamma-1
Uniport Id	P54619
Gene	PRKAG1
Gene Id	5571
Domain	CBS
Pfam	PF00571
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
3. Environmental Information Processing	3.2 Signal transduction	hsa04068	FoxO signaling pathway
3. Environmental Information Processing	3.2 Signal transduction	hsa04152	AMPK signaling pathway
5. Organismal Systems	5.9 Aging	hsa04211	Longevity regulating pathway
5. Organismal Systems	5.9 Aging	hsa04213	Longevity regulating pathway - multiple species
3. Environmental Information Processing	3.2 Signal transduction	hsa04371	Apelin signaling pathway
4. Cellular Processes	4.3 Cellular community - eukaryotes	hsa04530	Tight junction
5. Organismal Systems	5.10 Environmental adaptation	hsa04710	Circadian rhythm
5. Organismal Systems	5.10 Environmental adaptation	hsa04714	Thermogenesis
5. Organismal Systems	5.2 Endocrine system	hsa04910	Insulin signaling pathway
5. Organismal Systems	5.2 Endocrine system	hsa04920	Adipocytokine signaling pathway
5. Organismal Systems	5.2 Endocrine system	hsa04921	Oxytocin signaling pathway
5. Organismal Systems	5.2 Endocrine system	hsa04922	Glucagon signaling pathway
6. Human Diseases	6.7 Endocrine and metabolic diseases	hsa04931	Insulin resistance
6. Human Diseases	6.7 Endocrine and metabolic diseases	hsa04932	Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases	6.6 Cardiovascular diseases	hsa05410	Hypertrophic cardiomyopathy (HCM)

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007050	cell cycle arrest
Biological Process	GO:0042149	cellular response to glucose starvation
Biological Process	GO:0006633	fatty acid biosynthetic process
Biological Process	GO:0051170	import into nucleus
Biological Process	GO:0016236	macroautophagy
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:0045860	positive regulation of protein kinase activity
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:0050790	regulation of catalytic activity
Biological Process	GO:0006110	regulation of glycolytic process
Biological Process	GO:0016241	regulation of macroautophagy
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator
Biological Process	GO:0007165	signal transduction
Biological Process	GO:0007283	spermatogenesis
molecular function	GO:0043531	ADP binding
molecular function	GO:0016208	AMP binding
molecular function	GO:0005524	ATP binding
molecular function	GO:0004691	cAMP-dependent protein kinase activity
molecular function	GO:0008603	cAMP-dependent protein kinase regulator activity
molecular function	GO:0004672	protein kinase activity
molecular function	GO:0019901	protein kinase binding
molecular function	GO:0019887	protein kinase regulator activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0016020	membrane
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0031588	nucleotide-activated protein kinase complex
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name
R-HSA-112314	Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315	Transmission across Chemical Synapses
R-HSA-112316	Neuronal System
R-HSA-1445148	Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1592230	Mitochondrial biogenesis
R-HSA-162582	Signal Transduction
R-HSA-1632852	Macroautophagy
R-HSA-1632852	Macroautophagy
R-HSA-165159	MTOR signalling
R-HSA-1852241	Organelle biogenesis and maintenance
R-HSA-199991	Membrane Trafficking
R-HSA-212436	Generic Transcription Pathway
R-HSA-2151209	Activation of PPARGC1A (PGC-1alpha) by phosphorylation
R-HSA-3700989	Transcriptional Regulation by TP53
R-HSA-380972	Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-438064	Post NMDA receptor activation events
R-HSA-442755	Activation of NMDA receptors and postsynaptic events
R-HSA-5628897	TP53 Regulates Metabolic Genes
R-HSA-5633007	Regulation of TP53 Activity
R-HSA-5653656	Vesicle-mediated transport
R-HSA-6804756	Regulation of TP53 Activity through Phosphorylation
R-HSA-73857	RNA Polymerase II Transcription
R-HSA-74160	Gene expression (Transcription)
R-HSA-9612973	Autophagy
R-HSA-9612973	Autophagy
R-HSA-9613354	Lipophagy
R-HSA-9619483	Activation of AMPK downstream of NMDARs
R-HSA-9663891	Selective autophagy

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0021704	BXGD001510	Intelligence	Behavior and Behavior Mechanisms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0392885	BXGD008071	High density lipoprotein measurement
C0427460	BXGD008616	Red cell distribution width determination
C0596887	BXGD009648	mathematical ability
C0871470	BXGD011316	Systolic Pressure
C1304746	BXGD012343	RDW - Red blood cell distribution width result
C1305855	BXGD012348	Body mass index

Target protein-related compounds

Compounds

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}