Showing entry for Ephrin type-B receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011077
Protein NameEphrin type-B receptor 2
Uniport IdP54763
GeneEphb2
Gene Id13844
DomainEphA2_TM; Ephrin_lbd; Ephrin_rec_like; fn3; Pkinase_Tyr; SAM_1
Pfam PF14575   PF01404   PF07699   PF00041   PF07714   PF00536  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0007413 axonal fasciculation
Biological Process GO:0007411 axon guidance
Biological Process GO:0048593 camera-type eye morphogenesis
Biological Process GO:0000902 cell morphogenesis
Biological Process GO:0021952 central nervous system projection neuron axonogenesis
Biological Process GO:0071679 commissural neuron axon guidance
Biological Process GO:0022038 corpus callosum development
Biological Process GO:0060996 dendritic spine development
Biological Process GO:0060997 dendritic spine morphogenesis
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0051389 inactivation of MAPKK activity
Biological Process GO:0042472 inner ear morphogenesis
Biological Process GO:0007612 learning
Biological Process GO:0007611 learning or memory
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0050771 negative regulation of axonogenesis
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:1904782 negative regulation of NMDA glutamate receptor activity
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0046580 negative regulation of Ras protein signal transduction
Biological Process GO:0106028 neuron projection retraction
Biological Process GO:0021631 optic nerve morphogenesis
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0016310 phosphorylation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0048170 positive regulation of long-term neuronal synaptic plasticity
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:1904783 positive regulation of NMDA glutamate receptor activity
Biological Process GO:1903078 positive regulation of protein localization to plasma membrane
Biological Process GO:0051965 positive regulation of synapse assembly
Biological Process GO:0031915 positive regulation of synaptic plasticity
Biological Process GO:0097104 postsynaptic membrane assembly
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0050770 regulation of axonogenesis
Biological Process GO:0030193 regulation of blood coagulation
Biological Process GO:0050878 regulation of body fluid levels
Biological Process GO:0048168 regulation of neuronal synaptic plasticity
Biological Process GO:0031290 retinal ganglion cell axon guidance
Biological Process GO:0060021 roof of mouth development
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
Biological Process GO:0001655 urogenital system development
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0005524 ATP binding
molecular function GO:0008046 axon guidance receptor activity
molecular function GO:0005003 ephrin receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0005005 transmembrane-ephrin receptor activity
molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005654 nucleoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein