Showing entry for Caspase-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011113
Protein NameCaspase-3
Uniport IdP55213
GeneCasp3
Gene Id25402
DomainPeptidase_C14
Pfam -  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061713 anterior neural tube closure
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007413 axonal fasciculation
Biological Process GO:0001782 B cell homeostasis
Biological Process GO:0045165 cell fate commitment
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0071407 cellular response to organic cyclic compound
Biological Process GO:0071310 cellular response to organic substance
Biological Process GO:0072734 cellular response to staurosporine
Biological Process GO:0030218 erythrocyte differentiation
Biological Process GO:0097194 execution phase of apoptosis
Biological Process GO:0034349 glial cell apoptotic process
Biological Process GO:0007507 heart development
Biological Process GO:0021766 hippocampus development
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress
Biological Process GO:0030216 keratinocyte differentiation
Biological Process GO:0007611 learning or memory
Biological Process GO:0071887 leukocyte apoptotic process
Biological Process GO:0001554 luteolysis
Biological Process GO:0046007 negative regulation of activated T cell proliferation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0030889 negative regulation of B cell proliferation
Biological Process GO:0045786 negative regulation of cell cycle
Biological Process GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0048011 neurotrophin TRK receptor signaling pathway
Biological Process GO:1902004 positive regulation of amyloid-beta formation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0016485 protein processing
Biological Process GO:0006508 proteolysis
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0043200 response to amino acid
Biological Process GO:0046677 response to antibiotic
Biological Process GO:0032025 response to cobalt ion
Biological Process GO:0042493 response to drug
Biological Process GO:0032355 response to estradiol
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0009749 response to glucose
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0010038 response to metal ion
Biological Process GO:0035094 response to nicotine
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010033 response to organic substance
Biological Process GO:0009411 response to UV
Biological Process GO:0009611 response to wounding
Biological Process GO:0010165 response to X-ray
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0051146 striated muscle cell differentiation
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0042060 wound healing
molecular function GO:0004190 aspartic-type endopeptidase activity
molecular function GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
molecular function GO:0004197 cysteine-type endopeptidase activity
molecular function GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
molecular function GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
molecular function GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis
molecular function GO:0008234 cysteine-type peptidase activity
molecular function GO:0005123 death receptor binding
molecular function GO:0008233 peptidase activity
molecular function GO:0016005 phospholipase A2 activator activity
molecular function GO:0002020 protease binding
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0031264 death-inducing signaling complex
cellular component GO:0045121 membrane raft
cellular component GO:0043025 neuronal cell body
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0008873 Xanthohumol 354.4
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein