Showing entry for Spike glycoprotein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011270
Protein NameSpike glycoprotein
Uniport IdP59594
GeneS
Gene Id1489668
DomainCorona_S2; Spike_NTD; Spike_rec_bind
Pfam PF01601   PF16451   PF09408  
OrganismHuman SARS coronavirus (SARS-CoV) (Severe acute respiratory syndrome coronavirus)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0075509 endocytosis involved in viral entry into host cell
Biological Process GO:0039654 fusion of virus membrane with host endosome membrane
Biological Process GO:0019064 fusion of virus membrane with host plasma membrane
Biological Process GO:0009405 pathogenesis
Biological Process GO:0046813 receptor-mediated virion attachment to host cell
Biological Process GO:0039587 suppression by virus of host tetherin activity
Biological Process GO:0039502 suppression by virus of host type I interferon-mediated signaling pathway
molecular function GO:0046789 host cell surface receptor binding
molecular function GO:0042802 identical protein binding
cellular component GO:0044173 host cell endoplasmic reticulum-Golgi intermediate compartment membrane
cellular component GO:0020002 host cell plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0019031 viral envelope
cellular component GO:0055036 virion membrane
Reactome
Pathway Id Pathway Name
R-HSA-1643685 Disease
R-HSA-5663205 Infectious disease
R-HSA-9678108 SARS-CoV-1 Infection
R-HSA-9678110 Attachment and Entry
R-HSA-9679506 SARS-CoV Infections
R-HSA-9679509 Virion Assembly and Release
R-HSA-9683686 Maturation of spike protein
R-HSA-9683701 Translation of structural proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0004275 Acetaldehyde 44.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0049447 acetate 59.01
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein