Showing entry for Cell division control protein 42 homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011342
Protein NameCell division control protein 42 homolog
Uniport IdP60953
GeneCDC42
Gene Id998
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04015 Rap1 signaling pathway
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
3. Environmental Information Processing 3.2 Signal transduction hsa04370 VEGF signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04660 T cell receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04666 Fc gamma R-mediated phagocytosis
5. Organismal Systems 5.1 Immune system hsa04670 Leukocyte transendothelial migration
5. Organismal Systems 5.6 Nervous system hsa04722 Neurotrophin signaling pathway
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
5. Organismal Systems 5.2 Endocrine system hsa04912 GnRH signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04933 AGE-RAGE signaling pathway in diabetic complications
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05100 Bacterial invasion of epithelial cells
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05131 Shigellosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05132 Salmonella infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05211 Renal cell carcinoma
6. Human Diseases 6.2 Cancers: Specific types hsa05212 Pancreatic cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0090135 actin filament branching
Biological Process GO:0007015 actin filament organization
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0007596 blood coagulation
Biological Process GO:0003161 cardiac conduction system development
Biological Process GO:0032488 Cdc42 protein signal transduction
Biological Process GO:0034329 cell junction assembly
Biological Process GO:0016477 cell migration
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0034613 cellular protein localization
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0036336 dendritic cell migration
Biological Process GO:0060997 dendritic spine morphogenesis
Biological Process GO:0006897 endocytosis
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0045198 establishment of epithelial cell apical/basal polarity
Biological Process GO:0051683 establishment of Golgi localization
Biological Process GO:0007163 establishment or maintenance of cell polarity
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0046847 filopodium assembly
Biological Process GO:0007030 Golgi organization
Biological Process GO:0060047 heart contraction
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0035722 interleukin-12-mediated signaling pathway
Biological Process GO:0030225 macrophage differentiation
Biological Process GO:0099563 modification of synaptic structure
Biological Process GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
Biological Process GO:0031333 negative regulation of protein-containing complex assembly
Biological Process GO:0048664 neuron fate determination
Biological Process GO:0038189 neuropilin signaling pathway
Biological Process GO:0007097 nuclear migration
Biological Process GO:0072384 organelle transport along microtubule
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:2000251 positive regulation of actin cytoskeleton reorganization
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0032467 positive regulation of cytokinesis
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:0090316 positive regulation of intracellular protein transport
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0010592 positive regulation of lamellipodium assembly
Biological Process GO:0051149 positive regulation of muscle cell differentiation
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Biological Process GO:0048549 positive regulation of pinocytosis
Biological Process GO:0031274 positive regulation of pseudopodium assembly
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Biological Process GO:0051835 positive regulation of synapse structural plasticity
Biological Process GO:0051988 regulation of attachment of spindle microtubules to kinetochore
Biological Process GO:0051489 regulation of filopodium assembly
Biological Process GO:0010591 regulation of lamellipodium assembly
Biological Process GO:0007088 regulation of mitotic nuclear division
Biological Process GO:0043393 regulation of protein binding
Biological Process GO:0051056 regulation of small GTPase mediated signal transduction
Biological Process GO:0051492 regulation of stress fiber assembly
Biological Process GO:0002040 sprouting angiogenesis
Biological Process GO:0060661 submandibular salivary gland formation
Biological Process GO:0021762 substantia nigra development
Biological Process GO:0031295 T cell costimulation
Biological Process GO:0048010 vascular endothelial growth factor receptor signaling pathway
Biological Process GO:0039694 viral RNA genome replication
Biological Process GO:0060071 Wnt signaling pathway, planar cell polarity pathway
molecular function GO:0034191 apolipoprotein A-I receptor binding
molecular function GO:0032427 GBD domain binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0030742 GTP-dependent protein binding
molecular function GO:0042802 identical protein binding
molecular function GO:0031435 mitogen-activated protein kinase kinase kinase binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0031996 thioesterase binding
molecular function GO:0061630 ubiquitin protein ligase activity
cellular component GO:0045177 apical part of cell
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0036464 cytoplasmic ribonucleoprotein granule
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0030175 filopodium
cellular component GO:0005925 focal adhesion
cellular component GO:0000139 Golgi membrane
cellular component GO:0017119 Golgi transport complex
cellular component GO:0031256 leading edge membrane
cellular component GO:0016020 membrane
cellular component GO:0005815 microtubule organizing center
cellular component GO:0030496 midbody
cellular component GO:0072686 mitotic spindle
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0030141 secretory granule
cellular component GO:0051233 spindle midzone
cellular component GO:0000322 storage vacuole
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114604 GPVI-mediated activation cascade
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-177929 Signaling by EGFR
R-HSA-182971 EGFR downregulation
R-HSA-194138 Signaling by VEGF
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194840 Rho GTPase cycle
R-HSA-195258 RHO GTPase Effectors
R-HSA-195258 RHO GTPase Effectors
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-372790 Signaling by GPCR
R-HSA-373752 Netrin-1 signaling
R-HSA-376176 Signaling by ROBO receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-388841 Costimulation by the CD28 family
R-HSA-389356 CD28 co-stimulation
R-HSA-389359 CD28 dependent Vav1 pathway
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-397795 G-protein beta:gamma signalling
R-HSA-418885 DCC mediated attractive signaling
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-428543 Inactivation of CDC42 and RAC1
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-447115 Interleukin-12 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-525793 Myogenesis
R-HSA-525793 Myogenesis
R-HSA-5625970 RHO GTPases activate KTN1
R-HSA-5626467 RHO GTPases activate IQGAPs
R-HSA-5627123 RHO GTPases activate PAKs
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
R-HSA-8964616 G beta:gamma signalling through CDC42
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9020591 Interleukin-12 signaling
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001624 BXGD000067 Adrenal Gland Neoplasms Neoplasms; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005818 BXGD000338 Blood Platelet Disorders Hemic and Lymphatic Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007873 BXGD000500 Uterine Cervical Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007959 BXGD000507 Charcot-Marie-Tooth Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010418 BXGD000671 Cryptosporidiosis Digestive System Diseases; Infections; Animal Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013371 BXGD000823 Shigella Infections Digestive System Diseases; Infections
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015310 BXGD000976 Exotropia Eye Diseases; Nervous System Diseases
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016059 BXGD001043 Fibrosis Pathological Conditions, Signs and Symptoms
C0017160 BXGD001099 Gastroenteritis Digestive System Diseases
C0017605 BXGD001126 Angle Closure Glaucoma Eye Diseases
C0017606 BXGD001127 Primary angle-closure glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018816 BXGD001234 Heart Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024236 BXGD001752 Lymphedema Hemic and Lymphatic Diseases
C0024266 BXGD001754 Lymphocytic Choriomeningitis Infections; Nervous System Diseases
C0024291 BXGD001757 Lymphohistiocytosis, Hemophagocytic Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024636 BXGD001793 Malocclusion Stomatognathic Diseases
C0024667 BXGD001794 Animal Mammary Neoplasms Neoplasms; Animal Diseases
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027540 BXGD001996 Necrosis Pathological Conditions, Signs and Symptoms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0027960 BXGD002062 Nevus Neoplasms
C0028326 BXGD002075 Noonan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028866 BXGD002094 Oculomotor Nerve Paralysis Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039292 BXGD002807 Tangier Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0043046 BXGD003024 Wasting Syndrome Nutritional and Metabolic Diseases
C0043119 BXGD003029 Werner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0043194 BXGD003036 Wiskott-Aldrich Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153014 BXGD003612 Non-arthropod borne lymphocytic choriomeningitis Infections; Nervous System Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0156344 BXGD003851 Endometriosis of ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0158570 BXGD003892 Vascular anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0162359 BXGD003939 Christ-Siemens-Touraine syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0162678 BXGD003974 Neurofibromatoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0175701 BXGD004007 Aarskog syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0221217 BXGD004408 Neck webbing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0221369 BXGD004453 Acquired Camptodactyly
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0239234 BXGD004974 Low set ears
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0240543 BXGD005042 Bulbous nose
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0265610 BXGD005555 Clinodactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265950 BXGD005588 Venous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266294 BXGD005644 Unilateral agenesis of kidney Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266449 BXGD005670 Congenital anomaly of brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases
C0266470 BXGD005678 Cerebellar Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0272139 BXGD006309 Erythrocytosis due to low atmospheric pressure Hemic and Lymphatic Diseases
C0277873 BXGD006483 Nasal Flaring
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0282606 BXGD006817 Myomatous neoplasm Neoplasms; Musculoskeletal Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333875 BXGD006972 High-Grade Squamous Intraepithelial Lesions Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334070 BXGD006986 Maturation defect
C0334246 BXGD007006 Squamous cell carcinoma, metastatic Neoplasms
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0341306 BXGD007401 Microvillus inclusion disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0349458 BXGD007906 Cervical intraepithelial neoplasia grade 1 Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0403397 BXGD008277 Steroid-resistant nephrotic syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0423109 BXGD008470 Upward slant of palpebral fissure
C0423110 BXGD008471 Downward slant of palpebral fissure
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426886 BXGD008594 Tapering fingers (finding)
C0431447 BXGD008690 Synophrys Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0431478 BXGD008692 Posteriorly rotated ear
C0432072 BXGD008718 Dysmorphic features
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0494261 BXGD009023 Combined immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0596848 BXGD009647 lipoprotein disorder Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600452 BXGD009708 Hepatopulmonary Syndrome Digestive System Diseases; Respiratory Tract Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685409 BXGD009810 Congenital Camptodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740279 BXGD009973 Cerebellar atrophy
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0741146 BXGD010024 anxiety acute
C0750887 BXGD010240 Adrenal Cancer Neoplasms; Endocrine System Diseases
C0751072 BXGD010312 Frontotemporal Lobar Degeneration Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920299 BXGD011465 Overriding toe Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1096367 BXGD011618 Increased mean platelet volume
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1142533 BXGD011758 Smooth philtrum
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257925 BXGD011814 Mammary Carcinoma, Animal Neoplasms; Animal Diseases
C1262211 BXGD011876 Diarrhoea predominant irritable bowel syndrome
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333001 BXGD012578 Childhood Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1337012 BXGD012875 Well-differentiated papillary mesothelioma Neoplasms
C1368683 BXGD012900 Epithelioma Neoplasms
C1411966 BXGD013047 Clostridium; difficile (disorder)
C1412000 BXGD013049 Mesenteric vascular insufficiency Digestive System Diseases; Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519787 BXGD013250 Undifferentiated Neuroblastoma Neoplasms
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1832446 BXGD013844 Sparse eyebrow
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1835801 BXGD014050 Eversion of lateral third of lower eyelids Eye Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837260 BXGD014214 Prominent forehead
C1839758 BXGD014402 Narrow forehead
C1843367 BXGD014576 Poor school performance
C1844813 BXGD014679 Widely spaced teeth
C1845987 BXGD014770 Neutropenia, Severe Congenital, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1849367 BXGD015046 Nasal bridge wide
C1850456 BXGD015146 Progressive microcephaly
C1853242 BXGD015322 Midface retrusion
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859778 BXGD015931 Postnatal growth retardation
C1860493 BXGD015987 Abnormality of the sternum
C1861324 BXGD016029 Short philtrum
C1862382 BXGD016125 SVEINSSON CHORIORETINAL ATROPHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1865014 BXGD016282 Long philtrum
C1865017 BXGD016283 Thin upper lip vermilion
C1865572 BXGD016331 Proximal placement of thumb
C1866195 BXGD016385 Downturned corners of mouth
C1868571 BXGD016508 Highly arched eyebrow
C1956257 BXGD016623 Pulmonary Stenosis Cardiovascular Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242776 BXGD017001 Plexiform leiomyoma
C2363741 BXGD017100 HIV-1 infection
C2673431 BXGD017202 Abnormality of the periventricular white matter Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2699541 BXGD017461 Cytokine Measurement
C2751260 BXGD017694 Macrothrombocytopenia Hemic and Lymphatic Diseases
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2931133 BXGD017964 Pediatric Crohn's disease Digestive System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2937220 BXGD018154 Congenital abnormality of vein Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3266102 BXGD018597 Steroid resistant nephrotic syndrome of childhood Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3278923 BXGD018748 Dilated ventricles (finding)
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3539920 BXGD019089 ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3809250 BXGD019578 ESTROGEN RESISTANCE
C3811918 BXGD019664 GRN-related frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887494 BXGD019881 ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C4021085 BXGD020544 Abnormality of brain morphology
C4021866 BXGD020823 obsolete Abnormal heart morphology
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4225222 BXGD022181 TAKENOUCHI-KOSAKI SYNDROME
C4289709 BXGD022496 DOCK8 Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4551482 BXGD023310 Adams-Oliver syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C4551485 BXGD023312 Clinodactyly
C4551517 BXGD023334 Flared nostrils abnormality
C4551583 BXGD023361 Cerebral cortical atrophy
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000194 Sanguinarine 332.33
BXGC0000436 Glycerol 92.09
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0012352 Chelerythrine 348.12
BXGC0023195 Betulin 442.38
BXGC0024261 Adenosine Phosphate 347.06
BXGC0025215 Lupeol 426.39
BXGC0039684 Berberine Chloride 336.12
BXGC0040305 Indirubin 262.07
BXGC0043055 Palmatine Chloride 352.15
BXGC0044218 demethyleneberberine 324.12
BXGC0048845 Guanosine Triphosphate 522.99
BXGC0049738 Dexibuprofen 206.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein