Showing entry for ADP-ribosylation factor 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011423
Protein NameADP-ribosylation factor 6
Uniport IdP62330
GeneARF6
Gene Id382
DomainArf
Pfam PF00025  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
5. Organismal Systems 5.1 Immune system hsa04666 Fc gamma R-mediated phagocytosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007049 cell cycle
Biological Process GO:0051301 cell division
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:0030866 cortical actin cytoskeleton organization
Biological Process GO:0032456 endocytic recycling
Biological Process GO:0090162 establishment of epithelial cell polarity
Biological Process GO:0097284 hepatocyte apoptotic process
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0001889 liver development
Biological Process GO:0099562 maintenance of postsynaptic density structure
Biological Process GO:0033028 myeloid cell apoptotic process
Biological Process GO:2000171 negative regulation of dendrite development
Biological Process GO:2000009 negative regulation of protein localization to cell surface
Biological Process GO:0048261 negative regulation of receptor-mediated endocytosis
Biological Process GO:0030838 positive regulation of actin filament polymerization
Biological Process GO:0120183 positive regulation of focal adhesion disassembly
Biological Process GO:0051549 positive regulation of keratinocyte migration
Biological Process GO:1903078 positive regulation of protein localization to plasma membrane
Biological Process GO:0050714 positive regulation of protein secretion
Biological Process GO:0034394 protein localization to cell surface
Biological Process GO:0036010 protein localization to endosome
Biological Process GO:0060998 regulation of dendritic spine development
Biological Process GO:0051489 regulation of filopodium assembly
Biological Process GO:0035020 regulation of Rac protein signal transduction
Biological Process GO:0097178 ruffle assembly
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0047485 protein N-terminus binding
molecular function GO:0031996 thioesterase binding
cellular component GO:0005938 cell cortex
cellular component GO:0032154 cleavage furrow
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0031901 early endosome membrane
cellular component GO:0030139 endocytic vesicle
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0031527 filopodium membrane
cellular component GO:0090543 Flemming body
cellular component GO:0005925 focal adhesion
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0098793 presynapse
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0001726 ruffle
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-6806834 Signaling by MET
R-HSA-8854214 TBC/RABGAPs
R-HSA-8856828 Clathrin-mediated endocytosis
R-HSA-8875656 MET receptor recycling
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039585 BXGD002821 Androgen-Insensitivity Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220756 BXGD004338 Niemann-Pick Disease, Type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0917800 BXGD011411 Epilepsy, Myoclonic, Infantile Nervous System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002144 Tetradecanoic acid 228.37
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0004275 Acetaldehyde 44.05
BXGC0006198 Citric acid 192.12
BXGC0042315 1,4-dioxane 88.05
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein