Showing entry for Gamma-aminobutyric acid receptor subunit beta-3



                       
General Target Information
BXGT IdBXGT011492
Protein NameGamma-aminobutyric acid receptor subunit beta-3
Uniport IdP63080
GeneGabrb3
Gene Id14402
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071420 cellular response to histamine
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0090102 cochlea development
Biological Process GO:0007214 gamma-aminobutyric acid signaling pathway
Biological Process GO:0060080 inhibitory postsynaptic potential
Biological Process GO:1904862 inhibitory synapse assembly
Biological Process GO:0060119 inner ear receptor cell development
Biological Process GO:0060384 innervation
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0050877 nervous system process
Biological Process GO:0048666 neuron development
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0043523 regulation of neuron apoptotic process
Biological Process GO:0060021 roof of mouth development
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0007165 signal transduction
Biological Process GO:0051932 synaptic transmission, GABAergic
molecular function GO:0035612 AP-2 adaptor complex binding
molecular function GO:0005254 chloride channel activity
molecular function GO:0004890 GABA-A receptor activity
molecular function GO:0022851 GABA-gated chloride ion channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
cellular component GO:0034707 chloride channel complex
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:1902711 GABA-A receptor complex
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0060077 inhibitory synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099060 integral component of postsynaptic specialization membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002867 Lappaurin 284.74
BXGC0003886 N-Demethyldiazepam 270.71
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0007438 L-1,2,3,4-Tetrahydro-beta-carboline-3-carboxylic acid 216.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein