Showing entry for Hemoglobin subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011615
Protein NameHemoglobin subunit beta
Uniport IdP68871
GeneHBB
Gene Id3043
DomainGlobin
Pfam PF00042  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05143 African trypanosomiasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05144 Malaria
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015701 bicarbonate transport
Biological Process GO:0007596 blood coagulation
Biological Process GO:0098869 cellular oxidant detoxification
Biological Process GO:0042744 hydrogen peroxide catabolic process
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0030185 nitric oxide transport
Biological Process GO:0015671 oxygen transport
Biological Process GO:0070527 platelet aggregation
Biological Process GO:0010942 positive regulation of cell death
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0070293 renal absorption
Biological Process GO:0042542 response to hydrogen peroxide
molecular function GO:0020037 heme binding
molecular function GO:0031721 hemoglobin alpha binding
molecular function GO:0030492 hemoglobin binding
molecular function GO:0046872 metal ion binding
molecular function GO:0043177 organic acid binding
molecular function GO:0019825 oxygen binding
molecular function GO:0005344 oxygen carrier activity
cellular component GO:0072562 blood microparticle
cellular component GO:0005829 cytosol
cellular component GO:0071682 endocytic vesicle lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0031838 haptoglobin-hemoglobin complex
cellular component GO:0005833 hemoglobin complex
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-1237044 Erythrocytes take up carbon dioxide and release oxygen
R-HSA-1247673 Erythrocytes take up oxygen and release carbon dioxide
R-HSA-1480926 O2/CO2 exchange in erythrocytes
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-2168880 Scavenging of heme from plasma
R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors
R-HSA-382551 Transport of small molecules
R-HSA-5653656 Vesicle-mediated transport
R-HSA-6798695 Neutrophil degranulation
R-HSA-9612973 Autophagy
R-HSA-9613829 Chaperone Mediated Autophagy
R-HSA-9615710 Late endosomal microautophagy
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010520 BXGD000675 Cyanosis Pathological Conditions, Signs and Symptoms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0013502 BXGD000848 Echinococcosis Infections
C0014772 BXGD000948 Red Blood Cell Count measurement
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018935 BXGD001252 Hematocrit procedure
C0018939 BXGD001253 Hematological Disease Hemic and Lymphatic Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019021 BXGD001266 Hemoglobin C Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019025 BXGD001267 Hemoglobin F Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019034 BXGD001268 Hemoglobin SC Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019045 BXGD001269 Hemoglobinopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0019340 BXGD001321 Herpes NOS Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020532 BXGD001420 Hypersplenism Hemic and Lymphatic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020626 BXGD001452 Hypoparathyroidism Endocrine System Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0023524 BXGD001681 Leukoencephalopathy, Progressive Multifocal Infections; Nervous System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0024530 BXGD001783 Malaria Infections
C0024535 BXGD001785 Malaria, Falciparum Infections
C0025637 BXGD001879 Methemoglobinemia Hemic and Lymphatic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027543 BXGD001997 Avascular necrosis of bone Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0028077 BXGD002069 Nyctalopia Eye Diseases
C0029422 BXGD002142 Osteochondrodysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0030554 BXGD002239 Paresthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031485 BXGD002303 Phenylketonurias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0032181 BXGD002332 Platelet Count measurement
C0032461 BXGD002356 Polycythemia Hemic and Lymphatic Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0033117 BXGD002396 Priapism Male Urogenital Diseases
C0033847 BXGD002437 Pseudoxanthoma Elasticum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035369 BXGD002543 Retroviridae Infections Infections
C0037054 BXGD002663 Sickle Cell Trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039730 BXGD002826 Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042487 BXGD002986 Venous Thrombosis Cardiovascular Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0085578 BXGD003190 Thalassemia Minor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0085660 BXGD003228 Aseptic necrosis Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0151699 BXGD003461 Intracranial Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152200 BXGD003557 Achromatopsia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0152264 BXGD003577 Familial erythrocytosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0154089 BXGD003701 Carcinoma in situ of penis Neoplasms; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C0162316 BXGD003936 Iron deficiency anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0200633 BXGD004040 Neutrophil count (procedure)
C0200637 BXGD004042 Monocyte count procedure
C0200638 BXGD004043 Eosinophil count procedure
C0200641 BXGD004044 Blood basophil count (lab test)
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0200695 BXGD004046 Fetal hemoglobin determination
C0202239 BXGD004087 Uric acid measurement (procedure)
C0206160 BXGD004166 Reticulocytosis Pathological Conditions, Signs and Symptoms
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220810 BXGD004346 Congenital defects
C0221019 BXGD004367 Sickle cell-beta-thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0232466 BXGD004543 Feeding difficulties
C0235574 BXGD004754 Intravascular hemolysis Pathological Conditions, Signs and Symptoms
C0238159 BXGD004888 Hemoglobin E disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0239941 BXGD005009 Persistence of hemoglobin F
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0241013 BXGD005075 Increased serum ferritin
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262444 BXGD005244 Abnormality of the dentition Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0263454 BXGD005309 Chloracne Skin and Connective Tissue Diseases
C0268306 BXGD005891 Unconjugated hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271901 BXGD006277 Microcytic hypochromic anemia (disorder) Hemic and Lymphatic Diseases
C0271979 BXGD006283 Thalassemia Intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271980 BXGD006284 beta^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271985 BXGD006285 Delta-Beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271986 BXGD006286 delta beta^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271987 BXGD006287 ^A^gamma delta beta^0^ thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271990 BXGD006288 delta-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271994 BXGD006290 Hereditary persistence of fetal hemoglobin thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272080 BXGD006300 Hemoglobin D disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272087 BXGD006303 Congenital Methemoglobinemia Hemic and Lymphatic Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0302845 BXGD006856 MCV - raised
C0342788 BXGD007552 Renal carnitine transport defect Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0349705 BXGD007952 Abnormal hemoglobin finding
C0410528 BXGD008430 Skeletal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0423109 BXGD008470 Upward slant of palpebral fissure
C0427460 BXGD008616 Red cell distribution width determination
C0472767 BXGD008918 Beta thalassemia intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0472777 BXGD008920 Hemoglobin E/beta thalassemia disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0497552 BXGD009067 Congenital neurologic anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0553699 BXGD009410 Heinz body observation
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0581384 BXGD009568 Chronic anemia Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0600228 BXGD009699 Cardiopulmonary Arrest Cardiovascular Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700225 BXGD009882 Serum creatinine raised Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C0700299 BXGD009885 Heinz Body Anemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0702157 BXGD009910 Thalassemia trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0750880 BXGD010239 Monocyte count result
C0751434 BXGD010439 Classical phenylketonuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0836924 BXGD010864 Thrombocytosis Hemic and Lymphatic Diseases
C0869532 BXGD011308 Beta thalassemia minor
C0878520 BXGD011366 beta Thalassemia, heterozygous Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0878521 BXGD011367 Beta thalassemia trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1264000 BXGD011907 Sickle cell-Hemoglobin O Arab disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1387532 BXGD012957 Chronic hemolytic anemia Hemic and Lymphatic Diseases
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1527405 BXGD013290 Erythrocytosis Hemic and Lymphatic Diseases
C1533163 BXGD013310 Disorder of cellular component of blood Pathological Conditions, Signs and Symptoms
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1836542 BXGD014129 Depressed nasal bridge
C1841621 BXGD014478 FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1
C1844383 BXGD014628 Recurrent bacterial infection Infections
C1848701 BXGD014967 Elevated hepatic transaminase
C1848934 BXGD014988 SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1858732 BXGD015826 Malar prominence
C1858990 BXGD015840 Beta Thalassemia, Dominant Inclusion Body Type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
C1955934 BXGD016614 Trichothiodystrophy Syndromes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1962966 BXGD016678 Retinopathy, CTCAE
C1963165 BXGD016685 Malabsorption, CTCAE
C1970028 BXGD016803 MALARIA, SUSCEPTIBILITY TO (finding)
C2347748 BXGD017041 Adult Erythroleukemia
C2697573 BXGD017429 Heinz-Ehrlich Body Measurement
C2732618 BXGD017556 Sessile Serrated Adenoma/Polyp
C2825560 BXGD017773 S-Beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C2873756 BXGD017818 Severe beta thalassemia
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3149631 BXGD018283 MELORHEOSTOSIS, ISOLATED
C3161174 BXGD018505 Hemoglobin H Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3161373 BXGD018512 Dominant thalassemia
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3274463 BXGD018652 Sickle Beta 0 Thalassemia
C3278865 BXGD018747 Pigment gallstones Digestive System Diseases
C3539781 BXGD019086 Progressive cGVHD
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665425 BXGD019286 Hemoglobin M Disease Hemic and Lymphatic Diseases
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3841459 BXGD019798 Hb H disease
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3887513 BXGD019887 Avascular necrosis Pathological Conditions, Signs and Symptoms
C3889261 BXGD020003 Other License Status
C3889873 BXGD020012 HEMOGLOBIN SAINT ETIENNE PHENOTYPE
C3889898 BXGD020014 HEMOGLOBIN C PHENOTYPE
C3891694 BXGD020032 HEMOGLOBIN TUBINGEN PHENOTYPE
C4016175 BXGD020284 HEMOGLOBIN HOUSTON PHENOTYPE
C4017494 BXGD020444 BETA-KNOSSOS-THALASSEMIA
C4017510 BXGD020445 BETA-MALAY-THALASSEMIA
C4017522 BXGD020446 BETA-SHOWA-YAKUSHIJI THALASSEMIA
C4017525 BXGD020447 BETA-PLUS-THALASSEMIA, DOMINANT
C4017528 BXGD020448 BETA-THALASSEMIA, LERMONTOV TYPE
C4020827 BXGD020484 Neonatal hemolytic anemia
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4021790 BXGD020782 Abnormality of the skeletal system
C4021797 BXGD020787 Abnormality of the thorax
C4023136 BXGD021119 Reduced alpha/beta synthesis ratio
C4023137 BXGD021120 Reduced beta/alpha synthesis ratio
C4024695 BXGD021372 Increased red cell sickling tendency
C4025630 BXGD021703 Abnormal bone structure
C4025735 BXGD021767 Nonspherocytic hemolytic anemia Hemic and Lymphatic Diseases
C4025749 BXGD021773 Abnormality of the spleen
C4025819 BXGD021808 Abnormality of the hypothalamus-pituitary axis
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4274391 BXGD022353 Dominant beta-thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4284047 BXGD022432 HEMOGLOBIN AUBENAS PHENOTYPE
C4284050 BXGD022433 HEMOGLOBIN GAMBARA PHENOTYPE
C4290046 BXGD022507 trachomatis
C4310971 BXGD022689 HB NIIGATA
C4310973 BXGD022690 BETA-THALASSEMIA INTERMEDIA, DOMINANT
C4321477 BXGD022752 Sickle Cell-SS Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4477095 BXGD022922 Increased lactate dehydrogenase activity
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4551637 BXGD023379 Erythrocytosis familial, 1 Hemic and Lymphatic Diseases
C4553018 BXGD023532 Avascular Necrosis, CTCAE
C4553297 BXGD023538 Cystic Echinocccosis Infections
C4693797 BXGD023615 METHEMOGLOBINEMIA, BETA TYPE
C4693822 BXGD023617 ERYTHROCYTOSIS, FAMILIAL, 6
C4694049 BXGD023627 HEMOGLOBIN M (RADOM) METHEMOGLOBINEMIA, BETA TYPE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
BXGC0000332 Fisetin 286.24
BXGC0000436 Glycerol 92.09
BXGC0000461 Tricetin 302.24
BXGC0000497 Vanillin 152.15
BXGC0000530 Hydroquinone 110.11
BXGC0000952 6-Oxocamphor 457.91
BXGC0002071 Apigenin 270.24
BXGC0002358 Allitridin 178.34
BXGC0002591 Potassium 39.1
BXGC0002594 1,2-(2-Propenyl)-disulfane 146.27
BXGC0002616 Copper 63.55
BXGC0002619 Di-2-propenyl-sulfane 114.21
BXGC0002682 Zinc 65.41
BXGC0002722 Nitrate 62
BXGC0003218 Foluene 92.14
BXGC0003705 Chloride 35.45
BXGC0003751 Cyanide 26.02
BXGC0004681 Hydrogen sulfide (H2S) 34.08
BXGC0005217 Di-2-propenyl tetrasulfide 210.4
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0005793 Baicalein 270.24
BXGC0005857 Isoginkgetin 566.51
BXGC0005982 Curcumin 368.38
BXGC0006193 Ellagic acid 302.19
BXGC0007185 Iron(III) diphosphate (Fe4(P2O7)3) 745.21
BXGC0008676 Haem 616.49
BXGC0011366 4-Thiocyanatophenol 151.19
BXGC0012430 Methyl (1S,15R,17S,18S,19R,20R)-6,18-Dimethoxy-17-(3,4,5-Trimethoxybenzoyl)Oxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 608.27
BXGC0013582 Curcumin 368.13
BXGC0014993 sebacic acid 202.12
BXGC0016470 Camptothecin 348.11
BXGC0019460 Hydroxycamptothecin 364.11
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0024729 Mercaptopurine 152.02
BXGC0039485 Rauwolfia Serpentina 352.18
BXGC0039791 fructose 180.06
BXGC0044200 Menadione 172.05
BXGC0046996 Thioguanine 167.03
BXGC0050471 Fluorouracil 130.02
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein