Showing entry for Mothers against decapentaplegic homolog 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011667
Protein NameMothers against decapentaplegic homolog 1
Uniport IdP70340
GeneSmad1
Gene Id17125
DomainMH1; MH2
Pfam PF03165   PF03166  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030509 BMP signaling pathway
Biological Process GO:0060348 bone development
Biological Process GO:0060038 cardiac muscle cell proliferation
Biological Process GO:0051216 cartilage development
Biological Process GO:0071773 cellular response to BMP stimulus
Biological Process GO:0071407 cellular response to organic cyclic compound
Biological Process GO:0009880 embryonic pattern specification
Biological Process GO:0007276 gamete generation
Biological Process GO:0030902 hindbrain development
Biological Process GO:0042592 homeostatic process
Biological Process GO:0006954 inflammatory response
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0001710 mesodermal cell fate commitment
Biological Process GO:0030901 midbrain development
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0002051 osteoblast fate commitment
Biological Process GO:0061036 positive regulation of cartilage development
Biological Process GO:0045597 positive regulation of cell differentiation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0045669 positive regulation of osteoblast differentiation
Biological Process GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
Biological Process GO:1903672 positive regulation of sprouting angiogenesis
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0042493 response to drug
Biological Process GO:0007183 SMAD protein complex assembly
Biological Process GO:0060395 SMAD protein signal transduction
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway
Biological Process GO:0001657 ureteric bud development
molecular function GO:0070410 co-SMAD binding
molecular function GO:0017151 DEAD/H-box RNA helicase binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0070411 I-SMAD binding
molecular function GO:0046872 metal ion binding
molecular function GO:0070878 primary miRNA binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005637 nuclear inner membrane
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
cellular component GO:0005667 transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein