Showing entry for Mu-type opioid receptor



                       
General Target Information
BXGT IdBXGT011862
Protein NameMu-type opioid receptor
Uniport IdP79350
GeneOPRM1
Gene Id281958
Domain7tm_1
Pfam PF00001  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0043951 negative regulation of cAMP-mediated signaling
Biological Process GO:0051481 negative regulation of cytosolic calcium ion concentration
Biological Process GO:0045019 negative regulation of nitric oxide biosynthetic process
Biological Process GO:0061358 negative regulation of Wnt protein secretion
Biological Process GO:0038003 opioid receptor signaling pathway
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0019233 sensory perception of pain
molecular function GO:0004979 beta-endorphin receptor activity
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0038047 morphine receptor activity
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0005768 endosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0011725 (-)-Morphine 285.34
BXGC0026391 Naloxone 327.15
BXGC0030901 Morphine 285.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein