Showing entry for Calpain-1 catalytic subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012210
Protein NameCalpain-1 catalytic subunit
Uniport IdP97571
GeneCapn1
Gene Id29153
DomainCalpain_III; EF-hand_8; Peptidase_C2
Pfam PF01067   PF00648  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0007420 brain development
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0060056 mammary gland involution
Biological Process GO:0030837 negative regulation of actin filament polymerization
Biological Process GO:1901223 negative regulation of NIK/NF-kappaB signaling
Biological Process GO:0010666 positive regulation of cardiac muscle cell apoptotic process
Biological Process GO:1903238 positive regulation of leukocyte tethering or rolling
Biological Process GO:0043117 positive regulation of vascular permeability
Biological Process GO:0016540 protein autoprocessing
Biological Process GO:0006508 proteolysis
Biological Process GO:0032801 receptor catabolic process
Biological Process GO:0050790 regulation of catalytic activity
Biological Process GO:1990776 response to angiotensin
Biological Process GO:0046685 response to arsenic-containing substance
Biological Process GO:0097264 self proteolysis
molecular function GO:0004198 calcium-dependent cysteine-type endopeptidase activity
molecular function GO:0005509 calcium ion binding
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0019899 enzyme binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein