Showing entry for Low-density lipoprotein receptor-related protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012227
Protein NameLow-density lipoprotein receptor-related protein 2
Uniport IdP98158
GeneLrp2
Gene Id29216
DomaincEGF; EGF_CA; FXa_inhibition; Ldl_recept_a; Ldl_recept_b
Pfam PF12662   PF07645   PF00057   PF00058  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0035904 aorta development
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0061642 chemoattraction of axon
Biological Process GO:0060982 coronary artery morphogenesis
Biological Process GO:0060976 coronary vasculature development
Biological Process GO:0020028 endocytic hemoglobin import into cell
Biological Process GO:0006897 endocytosis
Biological Process GO:0016197 endosomal transport
Biological Process GO:1904447 folate import across plasma membrane
Biological Process GO:0030900 forebrain development
Biological Process GO:0007507 heart development
Biological Process GO:0046879 hormone secretion
Biological Process GO:0008584 male gonad development
Biological Process GO:0030001 metal ion transport
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0030514 negative regulation of BMP signaling pathway
Biological Process GO:0010951 negative regulation of endopeptidase activity
Biological Process GO:0001843 neural tube closure
Biological Process GO:0140058 neuron projection arborization
Biological Process GO:0003148 outflow tract septum morphogenesis
Biological Process GO:0045807 positive regulation of endocytosis
Biological Process GO:0140077 positive regulation of lipoprotein transport
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:0070447 positive regulation of oligodendrocyte progenitor proliferation
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:0015031 protein transport
Biological Process GO:0061156 pulmonary artery morphogenesis
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0042493 response to drug
Biological Process GO:0044321 response to leptin
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0033280 response to vitamin D
Biological Process GO:0010165 response to X-ray
Biological Process GO:0003139 secondary heart field specification
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0045056 transcytosis
Biological Process GO:0060068 vagina development
Biological Process GO:0003223 ventricular compact myocardium morphogenesis
Biological Process GO:0003281 ventricular septum development
Biological Process GO:0006766 vitamin metabolic process
molecular function GO:0005509 calcium ion binding
molecular function GO:0051087 chaperone binding
molecular function GO:0008144 drug binding
molecular function GO:0030492 hemoglobin binding
molecular function GO:0042562 hormone binding
molecular function GO:0031994 insulin-like growth factor I binding
molecular function GO:0050750 low-density lipoprotein particle receptor binding
molecular function GO:0030165 PDZ domain binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0140318 protein transporter activity
molecular function GO:0017124 SH3 domain binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0035258 steroid hormone receptor binding
cellular component GO:0045177 apical part of cell
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0044295 axonal growth cone
cellular component GO:0005903 brush border
cellular component GO:0031526 brush border membrane
cellular component GO:0009986 cell surface
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0030139 endocytic vesicle
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005768 endosome
cellular component GO:0031904 endosome lumen
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005615 extracellular space
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein