Showing entry for DNA topoisomerase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012265
Protein NameDNA topoisomerase 1
Uniport IdP9WG49
GenetopA
Gene Id23490079;885608
DomainTopoisom_bac; Toprim; Toprim_C_rpt
Pfam PF01131   PF01751   PF13368  
OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006265 DNA topological change
Biological Process GO:0060701 negative regulation of ribonuclease activity
molecular function GO:0003677 DNA binding
molecular function GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
molecular function GO:0000287 magnesium ion binding
cellular component GO:0005618 cell wall
cellular component GO:0005829 cytosol
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0006368 Formic acid 46.03
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein