Showing entry for Isocitrate lyase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012372
Protein NameIsocitrate lyase
Uniport IdP9WKK7
Geneicl
Gene Id23493439;886291
DomainICL
Pfam PF00463  
OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0006097 glyoxylate cycle
Biological Process GO:0006102 isocitrate metabolic process
Biological Process GO:0009405 pathogenesis
Biological Process GO:0010034 response to acetate
Biological Process GO:0010447 response to acidic pH
Biological Process GO:0070542 response to fatty acid
Biological Process GO:0052572 response to host immune response
Biological Process GO:0075141 symbiont tolerance to host environment
Biological Process GO:0006099 tricarboxylic acid cycle
molecular function GO:0004451 isocitrate lyase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0046421 methylisocitrate lyase activity
molecular function GO:0035375 zymogen binding
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000969 Glyoxylic acid 74.04
BXGC0001380 Succinic acid 118.09
BXGC0002391 4-Hydroxy-2-oxobutanoic acid 118.09
BXGC0002588 Magnesium 24.31
BXGC0038275 Pyruvic Acid 88.02
BXGC0042596 Isoniazid 137.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein