Showing entry for Dihydrofolate reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012429
Protein NameDihydrofolate reductase
Uniport IdP9WNX1
GenefolA
Gene Id887777
DomainDHFR_1
Pfam PF00186  
OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046452 dihydrofolate metabolic process
Biological Process GO:0046655 folic acid metabolic process
Biological Process GO:0006545 glycine biosynthetic process
Biological Process GO:0006730 one-carbon metabolic process
Biological Process GO:0046654 tetrahydrofolate biosynthetic process
molecular function GO:0004146 dihydrofolate reductase activity
molecular function GO:0070401 NADP+ binding
molecular function GO:0050661 NADP binding
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0042596 Isoniazid 137.06
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein