Showing entry for 2-isopropylmalate synthase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012499
Protein Name2-isopropylmalate synthase
Uniport IdP9WQB3
GeneleuA
Gene Id23490010;885092
DomainHMGL-like; LeuA_dimer
Pfam PF00682   PF08502  
OrganismMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009098 leucine biosynthetic process
molecular function GO:0003852 2-isopropylmalate synthase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0030955 potassium ion binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005576 extracellular region
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
BXGC0005944 3-Methyl-2-oxobutanoic acid 116.12
BXGC0006215 4-Methyl-2-oxopentanoic acid 130.14
BXGC0032575 Leucine 131.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein