Showing entry for Focal adhesion kinase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012552
Protein NameFocal adhesion kinase 1
Uniport IdQ00944
GenePTK2
Gene Id396416
DomainFERM_M; FERM_N_2; Focal_AT; Pkinase_Tyr
Pfam PF00373   PF18038   PF03623   PF07714  
OrganismGallus gallus (Chicken)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007015 actin filament organization
Biological Process GO:0001525 angiogenesis
Biological Process GO:0060055 angiogenesis involved in wound healing
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0045087 innate immune response
Biological Process GO:2000811 negative regulation of anoikis
Biological Process GO:0010812 negative regulation of cell-substrate adhesion
Biological Process GO:0031953 negative regulation of protein autophosphorylation
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0051894 positive regulation of focal adhesion assembly
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0021852 pyramidal neuron migration
Biological Process GO:0030155 regulation of cell adhesion
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0035994 response to muscle stretch
Biological Process GO:0009268 response to pH
Biological Process GO:0007172 signal complex assembly
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0044319 wound healing, spreading of cells
molecular function GO:0005524 ATP binding
molecular function GO:0004198 calcium-dependent cysteine-type endopeptidase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005178 integrin binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0002020 protease binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0036064 ciliary basal body
cellular component GO:0005737 cytoplasm
cellular component GO:0043197 dendritic spine
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0005925 focal adhesion
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0042383 sarcolemma
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein