Showing entry for Glutamate receptor ionotropic, NMDA 2A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012554
Protein NameGlutamate receptor ionotropic, NMDA 2A
Uniport IdQ00959
GeneGrin2a
Gene Id24409
DomainANF_receptor; Lig_chan; Lig_chan-Glu_bd; NMDAR2_C
Pfam PF01094   PF00060   PF10613   PF10565  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001508 action potential
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0071359 cellular response to dsRNA
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0071396 cellular response to lipid
Biological Process GO:0071286 cellular response to magnesium ion
Biological Process GO:0071287 cellular response to manganese ion
Biological Process GO:0071294 cellular response to zinc ion
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0097061 dendritic spine organization
Biological Process GO:0033058 directional locomotion
Biological Process GO:0042417 dopamine metabolic process
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0021766 hippocampus development
Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway
Biological Process GO:0007612 learning
Biological Process GO:0007611 learning or memory
Biological Process GO:0040011 locomotion
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0007613 memory
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0042177 negative regulation of protein catabolic process
Biological Process GO:0022008 neurogenesis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010942 positive regulation of cell death
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:1903539 protein localization to postsynaptic membrane
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0060078 regulation of postsynaptic membrane potential
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0014075 response to amine
Biological Process GO:0060359 response to ammonium ion
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0009743 response to carbohydrate
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0060992 response to fungicide
Biological Process GO:0009416 response to light stimulus
Biological Process GO:0010042 response to manganese ion
Biological Process GO:0051597 response to methylmercury
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0051707 response to other organism
Biological Process GO:0009611 response to wounding
Biological Process GO:0048511 rhythmic process
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042428 serotonin metabolic process
Biological Process GO:0030431 sleep
Biological Process GO:0021510 spinal cord development
Biological Process GO:0001964 startle response
Biological Process GO:0008542 visual learning
molecular function GO:0051117 ATPase binding
molecular function GO:0005262 calcium channel activity
molecular function GO:0005261 cation channel activity
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0016595 glutamate binding
molecular function GO:0022849 glutamate-gated calcium ion channel activity
molecular function GO:0035254 glutamate receptor binding
molecular function GO:0004970 ionotropic glutamate receptor activity
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
molecular function GO:0042165 neurotransmitter binding
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0022843 voltage-gated cation channel activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0009986 cell surface
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0043197 dendritic spine
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043005 neuron projection
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0098688 parallel fiber to Purkinje cell synapse
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0000436 Glycerol 92.09
BXGC0001642 Tricholomic acid 160.13
BXGC0002390 Spermine 202.34
BXGC0003113 N-trans-p-Coumaroyltyramine 283.32
BXGC0003296 1,3-Diaminopropane 74.12
BXGC0003566 2-Aminoadipic acid 161.16
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005794 Benzylamine 107.15
BXGC0006162 L-Glutamic acid 147.13
BXGC0006186 L-Aspartic acid 133.1
BXGC0006272 D-2-Aminobutanoic acid 103.12
BXGC0008059 1-Aminocyclopropanecarboxylic acid 101.1
BXGC0014659 D-Alanine 89.05
BXGC0020954 2-phenylquinoline 205.09
BXGC0024569 (1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0025204 Anthraquinone 208.05
BXGC0025485 Transtorine 189.04
BXGC0029437 (1R,2S)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0030028 (D)-Serine 105.04
BXGC0035865 (+)-Pentazocine 285.21
BXGC0036441 Quisqualate 189.04
BXGC0038154 D-Aspartate 133.04
BXGC0042317 5-methoxyindole-2-carboxylic acid 191.06
BXGC0042510 Fluoxetine 309.13
BXGC0042574 Ibogaine 310.2
BXGC0049516 Kainic Acid 213.1
BXGC0053391 N-(4-Hydroxyphenethyl)Cinnamamide 267.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein