Showing entry for Protein farnesyltransferase subunit beta



                       
General Target Information
BXGT IdBXGT012648
Protein NameProtein farnesyltransferase subunit beta
Uniport IdQ02293
GeneFntb
Gene Id64511
DomainPrenyltrans
Pfam PF00432  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0045787 positive regulation of cell cycle
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
Biological Process GO:0018343 protein farnesylation
Biological Process GO:0018342 protein prenylation
Biological Process GO:0048145 regulation of fibroblast proliferation
Biological Process GO:0034097 response to cytokine
Biological Process GO:0010035 response to inorganic substance
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0042060 wound healing
molecular function GO:0004311 farnesyltranstransferase activity
molecular function GO:0004660 protein farnesyltransferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005875 microtubule associated complex
cellular component GO:0032991 protein-containing complex
cellular component GO:0005965 protein farnesyltransferase complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0002588 Magnesium 24.31
BXGC0004277 Acetic acid 60.05
BXGC0045257 Lonafarnib 636.05
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein