Showing entry for Ephrin type-A receptor 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012695
Protein NameEphrin type-A receptor 4
Uniport IdQ03137
GeneEpha4
Gene Id13838
DomainEphA2_TM; Ephrin_lbd; fn3; Pkinase_Tyr; SAM_2
Pfam PF14575   PF01404   PF00041   PF07714   PF07647  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0007411 axon guidance
Biological Process GO:0007155 cell adhesion
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0090102 cochlea development
Biological Process GO:0021957 corticospinal tract morphogenesis
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0097156 fasciculation of motor neuron axon
Biological Process GO:0097155 fasciculation of sensory neuron axon
Biological Process GO:0008347 glial cell migration
Biological Process GO:0008045 motor neuron axon guidance
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0048681 negative regulation of axon regeneration
Biological Process GO:1900272 negative regulation of long-term synaptic potentiation
Biological Process GO:0010977 negative regulation of neuron projection development
Biological Process GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process
Biological Process GO:0072178 nephric duct morphogenesis
Biological Process GO:0106030 neuron projection fasciculation
Biological Process GO:0097485 neuron projection guidance
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:1902004 positive regulation of amyloid-beta formation
Biological Process GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
Biological Process GO:0050775 positive regulation of dendrite morphogenesis
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:2001108 positive regulation of Rho guanyl-nucleotide exchange factor activity
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0050821 protein stabilization
Biological Process GO:0048710 regulation of astrocyte differentiation
Biological Process GO:0050770 regulation of axonogenesis
Biological Process GO:0061001 regulation of dendritic spine morphogenesis
Biological Process GO:0043087 regulation of GTPase activity
Biological Process GO:1905244 regulation of modification of synaptic structure
Biological Process GO:0098883 synapse pruning
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0097161 DH domain binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0005004 GPI-linked ephrin receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0016301 kinase activity
molecular function GO:0042731 PH domain binding
molecular function GO:0004672 protein kinase activity
molecular function GO:1990782 protein tyrosine kinase binding
molecular function GO:0005005 transmembrane-ephrin receptor activity
molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity
cellular component GO:0005912 adherens junction
cellular component GO:0030424 axon
cellular component GO:0044295 axonal growth cone
cellular component GO:0043679 axon terminus
cellular component GO:0044297 cell body
cellular component GO:0042995 cell projection
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0043198 dendritic shaft
cellular component GO:0043197 dendritic spine
cellular component GO:0031901 early endosome membrane
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0030175 filopodium
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0005741 mitochondrial outer membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0043235 receptor complex
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein