Showing entry for Ephrin type-A receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012696
Protein NameEphrin type-A receptor 2
Uniport IdQ03145
GeneEpha2
Gene Id13836
DomainEphA2_TM; Ephrin_lbd; fn3; Pkinase_Tyr; SAM_1
Pfam PF14575   PF01404   PF00041   PF07714   PF00536  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0048320 axial mesoderm formation
Biological Process GO:0007411 axon guidance
Biological Process GO:0001568 blood vessel development
Biological Process GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis
Biological Process GO:0048514 blood vessel morphogenesis
Biological Process GO:0046849 bone remodeling
Biological Process GO:0060444 branching involved in mammary gland duct morphogenesis
Biological Process GO:0046058 cAMP metabolic process
Biological Process GO:0007155 cell adhesion
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:0016477 cell migration
Biological Process GO:0048870 cell motility
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0006954 inflammatory response
Biological Process GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process GO:0030216 keratinocyte differentiation
Biological Process GO:0070309 lens fiber cell morphogenesis
Biological Process GO:0033598 mammary gland epithelial cell proliferation
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0032682 negative regulation of chemokine production
Biological Process GO:0001818 negative regulation of cytokine production
Biological Process GO:1901491 negative regulation of lymphangiogenesis
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:0021915 neural tube development
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0060035 notochord cell development
Biological Process GO:0014028 notochord formation
Biological Process GO:0048570 notochord morphogenesis
Biological Process GO:0001649 osteoblast differentiation
Biological Process GO:0030316 osteoclast differentiation
Biological Process GO:1904238 pericyte cell differentiation
Biological Process GO:1903348 positive regulation of bicellular tight junction assembly
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:1903078 positive regulation of protein localization to plasma membrane
Biological Process GO:0036342 post-anal tail morphogenesis
Biological Process GO:0043491 protein kinase B signaling
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0045765 regulation of angiogenesis
Biological Process GO:0043535 regulation of blood vessel endothelial cell migration
Biological Process GO:0033628 regulation of cell adhesion mediated by integrin
Biological Process GO:0070372 regulation of ERK1 and ERK2 cascade
Biological Process GO:0010591 regulation of lamellipodium assembly
Biological Process GO:0070848 response to growth factor
Biological Process GO:0001501 skeletal system development
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0001570 vasculogenesis
molecular function GO:0005524 ATP binding
molecular function GO:0005005 transmembrane-ephrin receptor activity
molecular function GO:0004714 transmembrane receptor protein tyrosine kinase activity
cellular component GO:0009986 cell surface
cellular component GO:0005925 focal adhesion
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0030027 lamellipodium
cellular component GO:0031258 lamellipodium membrane
cellular component GO:0031256 leading edge membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
cellular component GO:0032587 ruffle membrane
cellular component GO:0070160 tight junction
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0037407 Lithocholic Acid 376.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein