Showing entry for Tyrosine-protein kinase ITK/TSK


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012724
Protein NameTyrosine-protein kinase ITK/TSK
Uniport IdQ03526
GeneItk
Gene Id16428
DomainBTK; PH; Pkinase_Tyr; SH2; SH3_1
Pfam PF00779   PF00169   PF07714   PF00017   PF00018  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0001816 cytokine production
Biological Process GO:0046629 gamma-delta T cell activation
Biological Process GO:0032609 interferon-gamma production
Biological Process GO:0032633 interleukin-4 production
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0001865 NK T cell differentiation
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0050852 T cell receptor signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
cellular component GO:0005911 cell-cell junction
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein