Showing entry for Sphingomyelin phosphodiesterase



                       
General Target Information
BXGT IdBXGT012767
Protein NameSphingomyelin phosphodiesterase
Uniport IdQ04519
GeneSmpd1
Gene Id20597
DomainMetallophos
Pfam PF00149  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046513 ceramide biosynthetic process
Biological Process GO:0006672 ceramide metabolic process
Biological Process GO:0008203 cholesterol metabolic process
Biological Process GO:0043407 negative regulation of MAP kinase activity
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0035307 positive regulation of protein dephosphorylation
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0006685 sphingomyelin catabolic process
Biological Process GO:0023021 termination of signal transduction
molecular function GO:0061750 acid sphingomyelin phosphodiesterase activity
molecular function GO:0016798 hydrolase activity, acting on glycosyl bonds
molecular function GO:0008081 phosphoric diester hydrolase activity
molecular function GO:0004767 sphingomyelin phosphodiesterase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005768 endosome
cellular component GO:0005615 extracellular space
cellular component GO:0042599 lamellar body
cellular component GO:0005764 lysosome
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein