Showing entry for Inter-alpha-trypsin inhibitor heavy chain H3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012853
Protein NameInter-alpha-trypsin inhibitor heavy chain H3
Uniport IdQ06033
GeneITIH3
Gene Id3699
DomainITI_HC_C; VIT; VWA
Pfam PF06668   PF08487   PF00092  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030212 hyaluronan metabolic process
Biological Process GO:0002576 platelet degranulation
molecular function GO:0004866 endopeptidase inhibitor activity
molecular function GO:0004867 serine-type endopeptidase inhibitor activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0031089 platelet dense granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001948 BXGD000091 Alcohol consumption Behavior and Behavior Mechanisms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005890 BXGD000345 Body Height
C0008074 BXGD000519 Child Development Disorders, Pervasive Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042018 BXGD002947 Urinary Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1305855 BXGD012348 Body mass index
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein