Showing entry for Exosome complex exonuclease DIS3



                       
General Target Information
BXGT IdBXGT012960
Protein NameExosome complex exonuclease DIS3
Uniport IdQ08162
GeneDIS3
Gene Id854138
DomainOB_Dis3; PIN_4; RNB; Rrp44_CSD1; Rrp44_S1
Pfam PF17849   PF13638   PF00773   PF17216   PF17215  
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process GO:0006397 mRNA processing
Biological Process GO:0043628 ncRNA 3'-end processing
Biological Process GO:0070651 nonfunctional rRNA decay
Biological Process GO:0071028 nuclear mRNA surveillance
Biological Process GO:0071039 nuclear polyadenylation-dependent CUT catabolic process
Biological Process GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process
Biological Process GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
Biological Process GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process
Biological Process GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
Biological Process GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay
Biological Process GO:0071051 polyadenylation-dependent snoRNA 3'-end processing
Biological Process GO:0016075 rRNA catabolic process
molecular function GO:0000175 3'-5'-exoribonuclease activity
molecular function GO:0004519 endonuclease activity
molecular function GO:0004521 endoribonuclease activity
molecular function GO:0000049 tRNA binding
cellular component GO:0000177 cytoplasmic exosome (RNase complex)
cellular component GO:0000178 exosome (RNase complex)
cellular component GO:0005739 mitochondrion
cellular component GO:0000176 nuclear exosome (RNase complex)
cellular component GO:0005730 nucleolus
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein