Showing entry for Phosphatidylcholine translocator ABCB4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012967
Protein NamePhosphatidylcholine translocator ABCB4
Uniport IdQ08201
GeneAbcb4
Gene Id24891
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032782 bile acid secretion
Biological Process GO:1903413 cellular response to bile acid
Biological Process GO:0099040 ceramide translocation
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0032376 positive regulation of cholesterol transport
Biological Process GO:0061092 positive regulation of phospholipid translocation
Biological Process GO:2001140 positive regulation of phospholipid transport
Biological Process GO:0042493 response to drug
Biological Process GO:1901557 response to fenofibrate
Biological Process GO:0051384 response to glucocorticoid
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0090554 phosphatidylcholine floppase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030136 clathrin-coated vesicle
cellular component GO:0005737 cytoplasm
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0046581 intercellular canaliculus
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030138 Colchicine 399.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein