Showing entry for Transcription factor GATA-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012983
Protein NameTranscription factor GATA-4
Uniport IdQ08369
GeneGata4
Gene Id14463
DomainGATA; GATA-N
Pfam PF00320   PF05349  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0003180 aortic valve morphogenesis
Biological Process GO:0060413 atrial septum morphogenesis
Biological Process GO:0003289 atrial septum primum morphogenesis
Biological Process GO:0003290 atrial septum secundum morphogenesis
Biological Process GO:0036302 atrioventricular canal development
Biological Process GO:0003190 atrioventricular valve formation
Biological Process GO:0003181 atrioventricular valve morphogenesis
Biological Process GO:0055007 cardiac muscle cell differentiation
Biological Process GO:0014898 cardiac muscle hypertrophy in response to stress
Biological Process GO:0048738 cardiac muscle tissue development
Biological Process GO:0061026 cardiac muscle tissue regeneration
Biological Process GO:0003215 cardiac right ventricle morphogenesis
Biological Process GO:0003279 cardiac septum development
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0045165 cell fate commitment
Biological Process GO:0061049 cell growth involved in cardiac muscle cell development
Biological Process GO:0071372 cellular response to follicle-stimulating hormone stimulus
Biological Process GO:0071371 cellular response to gonadotropin stimulus
Biological Process GO:0060540 diaphragm morphogenesis
Biological Process GO:0048557 embryonic digestive tract morphogenesis
Biological Process GO:0048617 embryonic foregut morphogenesis
Biological Process GO:0035054 embryonic heart tube anterior/posterior pattern specification
Biological Process GO:0035050 embryonic heart tube development
Biological Process GO:0048598 embryonic morphogenesis
Biological Process GO:0003197 endocardial cushion development
Biological Process GO:0001706 endoderm formation
Biological Process GO:0072148 epithelial cell fate commitment
Biological Process GO:0001702 gastrulation with mouth forming second
Biological Process GO:0007507 heart development
Biological Process GO:0001947 heart looping
Biological Process GO:0003007 heart morphogenesis
Biological Process GO:0060575 intestinal epithelial cell differentiation
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0060464 lung lobe formation
Biological Process GO:0060425 lung morphogenesis
Biological Process GO:0008584 male gonad development
Biological Process GO:0003192 mitral valve formation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:2001234 negative regulation of apoptotic signaling pathway
Biological Process GO:0010507 negative regulation of autophagy
Biological Process GO:0010667 negative regulation of cardiac muscle cell apoptotic process
Biological Process GO:1905204 negative regulation of connective tissue replacement
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:1903202 negative regulation of oxidative stress-induced cell death
Biological Process GO:0003151 outflow tract morphogenesis
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0030513 positive regulation of BMP signaling pathway
Biological Process GO:0060045 positive regulation of cardiac muscle cell proliferation
Biological Process GO:0051891 positive regulation of cardioblast differentiation
Biological Process GO:0045787 positive regulation of cell cycle
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0010575 positive regulation of vascular endothelial growth factor production
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0060043 regulation of cardiac muscle cell proliferation
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0051896 regulation of protein kinase B signaling
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0042493 response to drug
Biological Process GO:0043627 response to estrogen
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0072520 seminiferous tubule development
Biological Process GO:0060008 Sertoli cell differentiation
Biological Process GO:0023019 signal transduction involved in regulation of gene expression
Biological Process GO:0035914 skeletal muscle cell differentiation
Biological Process GO:0060395 SMAD protein signal transduction
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0060290 transdifferentiation
Biological Process GO:0003195 tricuspid valve formation
Biological Process GO:0035239 tube morphogenesis
Biological Process GO:0060979 vasculogenesis involved in coronary vascular morphogenesis
Biological Process GO:0003229 ventricular cardiac muscle tissue development
Biological Process GO:0003281 ventricular septum development
Biological Process GO:0042060 wound healing
molecular function GO:0033613 activating transcription factor binding
molecular function GO:0003682 chromatin binding
molecular function GO:0000987 cis-regulatory region sequence-specific DNA binding
molecular function GO:0070410 co-SMAD binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0051525 NFAT protein binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001085 RNA polymerase II transcription factor binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0016604 nuclear body
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005634 nucleus
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002071 Apigenin 270.24
BXGC0006635 Luteolin 286.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein