protein

Showing entry for Microphthalmia-associated transcription factor

General Target Information
BXGT Id	BXGT013011
Protein Name	Microphthalmia-associated transcription factor
Uniport Id	Q08874
Gene	Mitf
Gene Id	17342
Domain	DUF3371; HLH; MITF_TFEB_C_3_N
Pfam	PF11851 PF00010 PF15951
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0046849	bone remodeling
Biological Process	GO:0043010	camera-type eye development
Biological Process	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process
Biological Process	GO:0030154	cell differentiation
Biological Process	GO:0045165	cell fate commitment
Biological Process	GO:0030318	melanocyte differentiation
Biological Process	GO:0043066	negative regulation of apoptotic process
Biological Process	GO:0030336	negative regulation of cell migration
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II
Biological Process	GO:0030316	osteoclast differentiation
Biological Process	GO:0043473	pigmentation
Biological Process	GO:2000144	positive regulation of DNA-templated transcription, initiation
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:0045893	positive regulation of transcription, DNA-templated
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0065003	protein-containing complex assembly
Biological Process	GO:0042127	regulation of cell population proliferation
Biological Process	GO:0010468	regulation of gene expression
Biological Process	GO:0045670	regulation of osteoclast differentiation
Biological Process	GO:2001141	regulation of RNA biosynthetic process
Biological Process	GO:0006355	regulation of transcription, DNA-templated
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II
Biological Process	GO:0006351	transcription, DNA-templated
Biological Process	GO:0016055	Wnt signaling pathway
molecular function	GO:0003682	chromatin binding
molecular function	GO:0003677	DNA binding
molecular function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function	GO:0003700	DNA-binding transcription factor activity
molecular function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function	GO:0070888	E-box binding
molecular function	GO:0046983	protein dimerization activity
molecular function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function	GO:0043565	sequence-specific DNA binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005634	nucleus
cellular component	GO:0032991	protein-containing complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002906	Caffeic acid ester		284.31

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}