Showing entry for 5'-AMP-activated protein kinase catalytic subunit alpha-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013031
Protein Name5'-AMP-activated protein kinase catalytic subunit alpha-2
Uniport IdQ09137
GenePrkaa2
Gene Id78975
DomainAdenylateSensor; Pkinase
Pfam PF16579   PF00069  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006914 autophagy
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0031669 cellular response to nutrient levels
Biological Process GO:0071417 cellular response to organonitrogen compound
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0071380 cellular response to prostaglandin E stimulus
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0097009 energy homeostasis
Biological Process GO:0006633 fatty acid biosynthetic process
Biological Process GO:0055089 fatty acid homeostasis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0008610 lipid biosynthetic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0032007 negative regulation of TOR signaling
Biological Process GO:1904428 negative regulation of tubulin deacetylation
Biological Process GO:0010508 positive regulation of autophagy
Biological Process GO:1903829 positive regulation of cellular protein localization
Biological Process GO:0045821 positive regulation of glycolytic process
Biological Process GO:2000758 positive regulation of peptidyl-lysine acetylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0070507 regulation of microtubule cytoskeleton organization
Biological Process GO:0062028 regulation of stress granule assembly
Biological Process GO:0014823 response to activity
Biological Process GO:0031000 response to caffeine
Biological Process GO:0014850 response to muscle activity
Biological Process GO:0048511 rhythmic process
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0004679 AMP-activated protein kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0035174 histone serine kinase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0030674 protein-macromolecule adaptor activity
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0010494 cytoplasmic stress granule
cellular component GO:0030425 dendrite
cellular component GO:0043025 neuronal cell body
cellular component GO:0005654 nucleoplasm
cellular component GO:0031588 nucleotide-activated protein kinase complex
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
molecular function GO:0050405 acetyl-CoA carboxylase kinase activity
molecular function GO:0047322 hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004999 Benzothiazole 135.19
BXGC0015943 (3r)-5,7-dihydroxy-6,8-dimethyl-3-(4'-hydroxybenzyl)chroman-4-one 314.12
BXGC0020143 (3S)-3,5,7-Trihydroxy-3-(4-hydroxybenzyl)-6,8-dimethyl-2,3-dihydro-4H-1-benzopyran-4-one 330.11
BXGC0021972 2',4'-Dihydroxy-3'-methyl-6'-methoxy-omega-(4-hydroxyphenyl)propiophenone 302.12
BXGC0026032 (3r)-5,7-dihydroxy-6-methyl-8-methoxy-3-(4'-hydroxybenzyl)chroman-4-one 330.11
BXGC0038839 (3S)-3,5,7-Trihydroxy-3-(4-hydroxybenzyl)-6-methyl-8-methoxy-2,3-dihydro-4H-1-benzopyran-4-one 346.11
BXGC0047995 LPRP-Et-97543 300.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein