Showing entry for Tripartite motif-containing protein 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013138
Protein NameTripartite motif-containing protein 5
Uniport IdQ0PF16
GeneTRIM5
Gene Id574288
DomainSPRY; zf-B_box; zf-RING_UBOX
Pfam PF00622   PF00643   PF13445  
OrganismMacaca mulatta (Rhesus macaque)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002218 activation of innate immune response
Biological Process GO:0006914 autophagy
Biological Process GO:0051607 defense response to virus
Biological Process GO:0045087 innate immune response
Biological Process GO:0046597 negative regulation of viral entry into host cell
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:1902187 negative regulation of viral release from host cell
Biological Process GO:0032897 negative regulation of viral transcription
Biological Process GO:0010508 positive regulation of autophagy
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0070534 protein K63-linked ubiquitination
Biological Process GO:0000209 protein polyubiquitination
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway
Biological Process GO:0032880 regulation of protein localization
Biological Process GO:0046596 regulation of viral entry into host cell
molecular function GO:0042802 identical protein binding
molecular function GO:0038187 pattern recognition receptor activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0061630 ubiquitin protein ligase activity
molecular function GO:0004842 ubiquitin-protein transferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0000932 P-body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002722 Nitrate 62
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein