Showing entry for Sarcoplasmic/endoplasmic reticulum calcium ATPase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013178
Protein NameSarcoplasmic/endoplasmic reticulum calcium ATPase 1
Uniport IdQ0VCY0
GeneATP2A1
Gene Id518117
DomainCation_ATPase; Cation_ATPase_C; Cation_ATPase_N; E1-E2_ATPase
Pfam PF00689   PF00690  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008637 apoptotic mitochondrial changes
Biological Process GO:1990036 calcium ion import into sarcoplasmic reticulum
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0051659 maintenance of mitochondrion location
Biological Process GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:1901896 positive regulation of ATPase-coupled calcium transmembrane transporter activity
Biological Process GO:1902082 positive regulation of calcium ion import into sarcoplasmic reticulum
Biological Process GO:0106134 positive regulation of cardiac muscle cell contraction
Biological Process GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration
Biological Process GO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction
Biological Process GO:0051561 positive regulation of mitochondrial calcium ion concentration
Biological Process GO:0090076 relaxation of skeletal muscle
molecular function GO:0016887 ATPase activity
molecular function GO:0005524 ATP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism
cellular component GO:0016021 integral component of membrane
cellular component GO:0005739 mitochondrion
cellular component GO:0033017 sarcoplasmic reticulum membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein