Showing entry for 3-hydroxy-3-methylglutaryl-coenzyme A reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013197
Protein Name3-hydroxy-3-methylglutaryl-coenzyme A reductase
Uniport IdQ10283
Genehmg1
Gene Id2538999
DomainHMG-CoA_red; Sterol-sensing
Pfam PF00368   PF12349  
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015936 coenzyme A metabolic process
Biological Process GO:0006696 ergosterol biosynthetic process
Biological Process GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway
Biological Process GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
Biological Process GO:0008299 isoprenoid biosynthetic process
Biological Process GO:0016126 sterol biosynthetic process
molecular function GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
molecular function GO:0042282 hydroxymethylglutaryl-CoA reductase activity
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005635 nuclear envelope
cellular component GO:0031965 nuclear membrane
cellular component GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
cellular component GO:0005778 peroxisomal membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004131 trans-Isoasarone 208.25
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein