Showing entry for Disintegrin and metalloproteinase domain-containing protein 10


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013208
Protein NameDisintegrin and metalloproteinase domain-containing protein 10
Uniport IdQ10741
GeneADAM10
Gene Id282132
DomainDisintegrin; Pep_M12B_propep; Reprolysin_2
Pfam PF00200   PF01562  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0090102 cochlea development
Biological Process GO:0051089 constitutive protein ectodomain proteolysis
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0006509 membrane protein ectodomain proteolysis
Biological Process GO:0042117 monocyte activation
Biological Process GO:0007162 negative regulation of cell adhesion
Biological Process GO:0007219 Notch signaling pathway
Biological Process GO:0051088 PMA-inducible membrane protein ectodomain proteolysis
Biological Process GO:0046931 pore complex assembly
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010820 positive regulation of T cell chemotaxis
Biological Process GO:0099173 postsynapse organization
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0016485 protein processing
Biological Process GO:0098696 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
Biological Process GO:0008593 regulation of Notch signaling pathway
Biological Process GO:1901342 regulation of vasculature development
Biological Process GO:0034612 response to tumor necrosis factor
Biological Process GO:1901998 toxin transport
molecular function GO:0004175 endopeptidase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004222 metalloendopeptidase activity
molecular function GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0017124 SH3 domain binding
cellular component GO:0005912 adherens junction
cellular component GO:0030424 axon
cellular component GO:0009986 cell surface
cellular component GO:0030136 clathrin-coated vesicle
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005798 Golgi-associated vesicle
cellular component GO:0000139 Golgi membrane
cellular component GO:0005634 nucleus
cellular component GO:0097038 perinuclear endoplasmic reticulum
cellular component GO:0005886 plasma membrane
cellular component GO:0046930 pore complex
cellular component GO:0014069 postsynaptic density
cellular component GO:0097060 synaptic membrane
cellular component GO:0097197 tetraspanin-enriched microdomain
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein