Showing entry for Alpha-(1,3)-fucosyltransferase 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013216
Protein NameAlpha-(1,3)-fucosyltransferase 7
Uniport IdQ11130
GeneFUT7
Gene Id2529
DomainGlyco_transf_10; Glyco_tran_10_N
Pfam PF17039   PF00852  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
Biological Process GO:0006672 ceramide metabolic process
Biological Process GO:0007566 embryo implantation
Biological Process GO:0036065 fucosylation
Biological Process GO:0006954 inflammatory response
Biological Process GO:0002522 leukocyte migration involved in immune response
Biological Process GO:0002523 leukocyte migration involved in inflammatory response
Biological Process GO:0042355 L-fucose catabolic process
Biological Process GO:0097021 lymphocyte migration into lymphoid organs
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0022409 positive regulation of cell-cell adhesion
Biological Process GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell
Biological Process GO:1903238 positive regulation of leukocyte tethering or rolling
Biological Process GO:0006486 protein glycosylation
Biological Process GO:0060353 regulation of cell adhesion molecule production
Biological Process GO:0022407 regulation of cell-cell adhesion
Biological Process GO:0046626 regulation of insulin receptor signaling pathway
Biological Process GO:1903037 regulation of leukocyte cell-cell adhesion
Biological Process GO:1903236 regulation of leukocyte tethering or rolling
Biological Process GO:2000389 regulation of neutrophil extravasation
Biological Process GO:0001807 regulation of type IV hypersensitivity
molecular function GO:0017083 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity
molecular function GO:0046920 alpha-(1->3)-fucosyltransferase activity
molecular function GO:0008417 fucosyltransferase activity
cellular component GO:0005794 Golgi apparatus
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71387 Metabolism of carbohydrates
R-HSA-9033658 Blood group systems biosynthesis
R-HSA-9037629 Lewis blood group biosynthesis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1136382 BXGD011717 Sclerocystic Ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000057 3,4-Dimethoxybenzoic acid 182.17
BXGC0000251 Syringic acid 198.17
BXGC0000368 Gallic acid 170.12
BXGC0000369 Methyl gallate 184.15
BXGC0000500 2,4-Dihydroxybenzoic acid 154.12
BXGC0000502 Gentisic acid 154.12
BXGC0000505 Protocatechuic acid 154.12
BXGC0002976 ent-Epigallocatechin 3-gallate 458.37
BXGC0005763 Eudesmic acid 212.2
BXGC0005898 2,3-Dihydroxybenzoic acid 154.12
BXGC0033310 Epigalocatechin Gallate 458.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein