Showing entry for Interferon-induced protein with tetratricopeptide repeats 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013341
Protein NameInterferon-induced protein with tetratricopeptide repeats 5
Uniport IdQ13325
GeneIFIT5
Gene Id24138
DomainTPR_10; TPR_12; TPR_8
Pfam PF07719   PF13181  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051607 defense response to virus
Biological Process GO:0045087 innate immune response
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
molecular function GO:0003690 double-stranded DNA binding
molecular function GO:0008266 poly(U) RNA binding
molecular function GO:0003723 RNA binding
molecular function GO:0000339 RNA cap binding
molecular function GO:0003727 single-stranded RNA binding
molecular function GO:0000049 tRNA binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0045177 apical part of cell
cellular component GO:0005829 cytosol
cellular component GO:0005886 plasma membrane
cellular component GO:0032587 ruffle membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-909733 Interferon alpha/beta signaling
R-HSA-913531 Interferon Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0024793 BXGD001805 Marek Disease Infections; Immune System Diseases; Hemic and Lymphatic Diseases; Animal Diseases
C0027149 BXGD001979 Myxoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein