Showing entry for Protein OS-9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013355
Protein NameProtein OS-9
Uniport IdQ13438
GeneOS9
Gene Id10956
DomainPRKCSH
Pfam PF07915  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1904380 endoplasmic reticulum mannose trimming
Biological Process GO:1904153 negative regulation of retrograde protein transport, ER to cytosol
Biological Process GO:0006621 protein retention in ER lumen
Biological Process GO:0006605 protein targeting
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:0030970 retrograde protein transport, ER to cytosol
Biological Process GO:0055085 transmembrane transport
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0030246 carbohydrate binding
molecular function GO:0002020 protease binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0044322 endoplasmic reticulum quality control compartment
cellular component GO:0000836 Hrd1p ubiquitin ligase complex
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-382551 Transport of small molecules
R-HSA-382556 ABC-family proteins mediated transport
R-HSA-392499 Metabolism of proteins
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle
R-HSA-5358346 Hedgehog ligand biogenesis
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
R-HSA-5387390 Hh mutants abrogate ligand secretion
R-HSA-5619084 ABC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5678895 Defective CFTR causes cystic fibrosis
R-HSA-597592 Post-translational protein modification
R-HSA-901032 ER Quality Control Compartment (ERQC)
R-HSA-901042 Calnexin/calreticulin cycle
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0424621 BXGD008536 Body Fat Distribution
C1261473 BXGD011855 Sarcoma Neoplasms
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein