Showing entry for Tubulin beta-3 chain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013366
Protein NameTubulin beta-3 chain
Uniport IdQ13509
GeneTUBB3
Gene Id10381
DomainTubulin; Tubulin_C
Pfam PF00091   PF03953  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04540 Gap junction
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007411 axon guidance
Biological Process GO:1990791 dorsal root ganglion development
Biological Process GO:0007017 microtubule-based process
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0030182 neuron differentiation
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:1990890 netrin receptor binding
molecular function GO:0005200 structural constituent of cytoskeleton
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0070062 extracellular exosome
cellular component GO:0030175 filopodium
cellular component GO:0030426 growth cone
cellular component GO:0030027 lamellipodium
cellular component GO:0005874 microtubule
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1280218 Adaptive Immune System
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-157858 Gap junction trafficking and regulation
R-HSA-157858 Gap junction trafficking and regulation
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-1632852 Macroautophagy
R-HSA-1640170 Cell Cycle
R-HSA-1643685 Disease
R-HSA-168256 Immune System
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-190828 Gap junction trafficking
R-HSA-190828 Gap junction trafficking
R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
R-HSA-190861 Gap junction assembly
R-HSA-190861 Gap junction assembly
R-HSA-190872 Transport of connexons to the plasma membrane
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-199977 ER to Golgi Anterograde Transport
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-2132295 MHC class II antigen presentation
R-HSA-2262752 Cellular responses to stress
R-HSA-2467813 Separation of Sister Chromatids
R-HSA-2500257 Resolution of Sister Chromatid Cohesion
R-HSA-2555396 Mitotic Metaphase and Anaphase
R-HSA-2995410 Nuclear Envelope (NE) Reassembly
R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR)
R-HSA-373760 L1CAM interactions
R-HSA-373760 L1CAM interactions
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC
R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC
R-HSA-389977 Post-chaperonin tubulin folding pathway
R-HSA-390466 Chaperonin-mediated protein folding
R-HSA-391251 Protein folding
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-437239 Recycling pathway of L1
R-HSA-437239 Recycling pathway of L1
R-HSA-438064 Post NMDA receptor activation events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5617833 Cilium Assembly
R-HSA-5620924 Intraflagellar transport
R-HSA-5626467 RHO GTPases activate IQGAPs
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5663205 Infectious disease
R-HSA-5663220 RHO GTPases Activate Formins
R-HSA-597592 Post-translational protein modification
R-HSA-597592 Post-translational protein modification
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
R-HSA-68877 Mitotic Prometaphase
R-HSA-68882 Mitotic Anaphase
R-HSA-68886 M Phase
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint
R-HSA-8856688 Golgi-to-ER retrograde transport
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin
R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin
R-HSA-948021 Transport to the Golgi and subsequent modification
R-HSA-9609646 HCMV Infection
R-HSA-9609690 HCMV Early Events
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
R-HSA-9612973 Autophagy
R-HSA-9612973 Autophagy
R-HSA-9619483 Activation of AMPK downstream of NMDARs
R-HSA-9646399 Aggrephagy
R-HSA-9646399 Aggrephagy
R-HSA-9648025 EML4 and NUDC in mitotic spindle formation
R-HSA-9663891 Selective autophagy
R-HSA-9663891 Selective autophagy
R-HSA-9668328 Sealing of the nuclear envelope (NE) by ESCRT-III
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
R-HSA-983189 Kinesins
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002418 BXGD000112 Amblyopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0003962 BXGD000244 Ascites Pathological Conditions, Signs and Symptoms
C0004114 BXGD000255 Astrocytoma Neoplasms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014474 BXGD000917 Ependymoma Neoplasms
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0014877 BXGD000967 Esotropia Eye Diseases; Nervous System Diseases
C0015310 BXGD000976 Exotropia Eye Diseases; Nervous System Diseases
C0015469 BXGD000996 Facial paralysis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018498 BXGD001195 Hair Color
C0019825 BXGD001349 Hoarseness Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020258 BXGD001371 Hydrocephalus, Normal Pressure Nervous System Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020796 BXGD001468 Profound Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023051 BXGD001602 Laryngeal Diseases Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0023882 BXGD001710 Little's Disease Nervous System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028850 BXGD002092 Ocular Motility Disorders Eye Diseases; Nervous System Diseases
C0028945 BXGD002099 oligodendroglioma Neoplasms
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030186 BXGD002190 Paget Disease Extramammary Neoplasms
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038271 BXGD002742 Stereotyped Behavior Behavior and Behavior Mechanisms
C0038273 BXGD002743 Stereotypic Movement Disorder Mental Disorders
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040485 BXGD002871 Torticollis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042928 BXGD003014 Vocal Cord Paralysis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0085633 BXGD003216 Mood swings Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0150080 BXGD003402 Social Communication Disorder Mental Disorders
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152221 BXGD003561 Paralytic strabismus Eye Diseases; Nervous System Diseases
C0153382 BXGD003627 Malignant neoplasm of oropharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0158465 BXGD003887 Acquired cubitus valgus
C0162292 BXGD003930 External Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0162809 BXGD003981 Kallmann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205969 BXGD004143 Thymic Carcinoma Neoplasms; Hemic and Lymphatic Diseases
C0206658 BXGD004221 Smooth Muscle Tumor Neoplasms
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0206701 BXGD004251 Cystadenocarcinoma, Serous Neoplasms
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0221060 BXGD004384 Mobius Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Stomatognathic Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0234175 BXGD004630 Palmar reflex
C0234435 BXGD004667 Syncope, Tussive Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234649 BXGD004692 Abnormal saccadic eye movement
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0239043 BXGD004960 Difficulty chewing
C0239234 BXGD004974 Low set ears
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0262630 BXGD005262 Reduced concentration span Behavior and Behavior Mechanisms
C0265529 BXGD005542 Plagiocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266449 BXGD005670 Congenital anomaly of brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases
C0266463 BXGD005675 Lissencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266464 BXGD005676 Polymicrogyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266470 BXGD005678 Cerebellar Hypoplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0266617 BXGD005700 Congenital anomaly of face Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0271270 BXGD006178 Oculovestibuloauditory syndrome Eye Diseases; Nervous System Diseases; Cardiovascular Diseases
C0271623 BXGD006222 Hypogonadotropic hypogonadism Endocrine System Diseases
C0271682 BXGD006233 Mixed sensory-motor polyneuropathy Nervous System Diseases
C0276289 BXGD006418 Zika Virus Infection Infections
C0278488 BXGD006515 Carcinoma breast stage IV
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278874 BXGD006605 Adult Ependymoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0338502 BXGD007192 Hypoplasia of the optic nerve Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0345392 BXGD007732 Congenital kyphoscoliosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346975 BXGD007837 Secondary malignant neoplasm of rectum Digestive System Diseases; Neoplasms
C0376175 BXGD007981 Bell Palsy Infections; Nervous System Diseases; Stomatognathic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393593 BXGD008103 Dystonia Disorders Nervous System Diseases
C0393907 BXGD008154 Axonal sensorimotor neuropathy
C0423110 BXGD008471 Downward slant of palpebral fissure
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426970 BXGD008598 Spastic Quadriplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431368 BXGD008673 Partial agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431376 BXGD008678 Cobblestone Lissencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0431380 BXGD008680 Cortical Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0452138 BXGD008831 Sensorineural hearing loss, bilateral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0454641 BXGD008848 Expressive language delay
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0557874 BXGD009444 Global developmental delay
C0575158 BXGD009515 Kyphoscoliosis deformity of spine Musculoskeletal Diseases
C0575802 BXGD009521 Small hand
C0576093 BXGD009525 Knee joint valgus deformity Musculoskeletal Diseases
C0576226 BXGD009527 Short foot
C0600033 BXGD009682 Acquired Kyphoscoliosis Musculoskeletal Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677936 BXGD009737 Refractory cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0684337 BXGD009796 Ewings sarcoma-primitive neuroectodermal tumor (PNET) Neoplasms
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751396 BXGD010425 Well Differentiated Oligodendroglioma Neoplasms
C0796611 BXGD010835 Newly Diagnosed Childhood Ependymoma Neoplasms
C0861772 BXGD011252 Stage IV Rectal Carcinoma
C0917801 BXGD011412 Sleeplessness Nervous System Diseases; Mental Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1263857 BXGD011900 Peripheral axonal neuropathy Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1275278 BXGD012074 Extraskeletal Myxoid Chondrosarcoma Neoplasms
C1302995 BXGD012316 Congenital Fibrosis of the Extraocular Muscles Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1334953 BXGD012746 Neuroblastic tumors Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1511789 BXGD013183 Desmoplastic
C1514428 BXGD013203 Primary peritoneal carcinoma Digestive System Diseases; Neoplasms
C1527344 BXGD013275 Dysphonia Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1608408 BXGD013434 Malignant transformation
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1636149 BXGD013482 Macular dystrophy, corneal type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1706731 BXGD013576 Adult Extraskeletal Myxoid Chondrosarcoma Neoplasms
C1836217 BXGD014097 Tukel syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837397 BXGD014227 Severe global developmental delay
C1837402 BXGD014228 Flat occiput
C1840379 BXGD014459 Cerebellar vermis hypoplasia
C1842688 BXGD014532 Hypoplasia of the brainstem
C1846911 BXGD014847 Compensatory chin elevation
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1848673 BXGD014963 Hypoplastic feet
C1849156 BXGD015017 Spastic Ataxia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1849265 BXGD015028 Overgrowth
C1851087 BXGD015192 Agenesis of the anterior commissure
C1851102 BXGD015195 Fibrosis Of Extraocular Muscles, Congenital, 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C1851107 BXGD015196 Levator palpebrae superioris atrophy
C1851108 BXGD015197 Superior rectus atrophy
C1851584 BXGD015221 Childhood Ependymoma Neoplasms
C1851710 BXGD015226 LATERAL MENINGOCELE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1856409 BXGD015604 Dilation of lateral ventricles
C1857790 BXGD015748 Thoracic scoliosis Musculoskeletal Diseases
C1859470 BXGD015896 Large basal ganglia
C1859778 BXGD015931 Postnatal growth retardation
C1861403 BXGD016045 Variable expressivity
C1863753 BXGD016197 LIMB-MAMMARY SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1865915 BXGD016354 FIBROSIS OF EXTRAOCULAR MUSCLES, CONGENITAL, 2 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C1865916 BXGD016355 Bilateral ptosis Eye Diseases
C1955869 BXGD016612 Malformations of Cortical Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1963946 BXGD016707 Laryngeal dystonia Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1997740 BXGD016863 Segmental dystonia Nervous System Diseases
C2349952 BXGD017065 Oropharyngeal Carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2674608 BXGD017250 Feeding difficulties in infancy
C2677180 BXGD017366 Congenital microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2748801 BXGD017605 FIBROSIS OF EXTRAOCULAR MUSCLES, CONGENITAL, 3A, WITH OR WITHOUT EXTRAOCULAR INVOLVEMENT Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C2749675 BXGD017631 Cortical gyral simplification
C2750404 BXGD017658 Fibrosis of Extraocular Muscles, Congenital, 3C Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C2750737 BXGD017675 DIARRHEA 5, WITH TUFTING ENTEROPATHY, CONGENITAL Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Nutritional and Metabolic Diseases
C2751105 BXGD017692 FIBROSIS OF EXTRAOCULAR MUSCLES, CONGENITAL, 3B (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3489733 BXGD018945 Oculomotor apraxia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases; Behavior and Behavior Mechanisms; Cardiovascular Diseases
C3665346 BXGD019278 Unspecified visual loss Pathological Conditions, Signs and Symptoms; Eye Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665386 BXGD019284 Abnormal vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3806604 BXGD019520 Infantile axial hypotonia
C3808397 BXGD019545 CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 1
C4015552 BXGD020212 FIBROSIS OF EXTRAOCULAR MUSCLES, CONGENITAL, 5
C4021243 BXGD020593 Abnormality of thalamus morphology
C4022769 BXGD020994 Small basal ganglia
C4022906 BXGD021033 Delayed social development
C4023681 BXGD021239 Delayed fine motor development
C4024789 BXGD021418 Nonprogressive restrictive external ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4049830 BXGD021953 Focal seizures, afebril Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4073008 BXGD022033 Abnormal best corrected visual acuity test
C4082169 BXGD022084 Metatarsus Varus Musculoskeletal Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4476591 BXGD022835 Dysgenesis of the hippocampus
C4476710 BXGD022851 Delayed ability to sit
C4477049 BXGD022910 Hypoplasia of the olfactory bulb
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4553743 BXGD023548 Spasticity, CTCAE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721208 BXGD023733 Metastatic castration-resistant prostate cancer
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722419 BXGD023802 Extrapulmonary Small Cell Carcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000303 Eupatilin 344.32
BXGC0001403 5-Hydroxy-3,3',4',6,7,8-hexamethoxyflavone 418.39
BXGC0002018 Morin 302.24
BXGC0002588 Magnesium 24.31
BXGC0002953 2-Phenethyl isothiocyanate 163.24
BXGC0003452 Pectolinarigenin 314.29
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005559 3',4',5'-Trimethoxyflavone 312.32
BXGC0005982 Curcumin 368.38
BXGC0008937 Demethylnobiletin 388.37
BXGC0009047 3-Methoxynobiletin 432.42
BXGC0013582 Curcumin 368.13
BXGC0014531 5,7-Dihydroxy-3,3',4',6-Tetramethoxyflavone 374.1
BXGC0019511 Ternatin 374.1
BXGC0022140 Combretastatin 334.14
BXGC0024799 Cornigerine 383.14
BXGC0024985 (-)-Demecolcine 371.17
BXGC0025658 Vinblastine 810.42
BXGC0025812 5,4'dihydroxy-3,6,7,8,3'-Pentamethoxyflavone 404.11
BXGC0026758 Santin 344.09
BXGC0027421 Paclitaxel 853.33
BXGC0028043 Arenastatin A 606.29
BXGC0028710 Kokusaginine 259.08
BXGC0030138 Colchicine 399.17
BXGC0031622 Podofilox 414.13
BXGC0032244 10-deacetyltaxol 811.32
BXGC0033365 Gardenin 418.13
BXGC0034768 Vincristine 824.4
BXGC0034865 2-(3,4-Dimethoxyphenyl)-3-Hydroxy-5,7-Dimethoxychromen-4-One 358.11
BXGC0034941 Combretastatin A4 316.13
BXGC0035119 Cryptophycin A 654.27
BXGC0036123 Ayanin 344.09
BXGC0038619 5,7-Dihydroxy-2-(4-Hydroxy-3-Methoxyphenyl)-3,6,8-Trimethoxychromen-4-One 390.1
BXGC0039971 3',5,7-Trihydroxy-3,4',5',6-Tetramethoxyflavone 390.1
BXGC0040019 2-Methoxy-5-(3,4,5-Trimethoxyphenethyl)Phenol 318.15
BXGC0040228 4'-Demethyldeoxypodophyllotoxin 384.12
BXGC0040364 Artesunate 384.18
BXGC0044329 5-Hydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-3,6,7,8-Tetramethoxychromen-4-One 404.11
BXGC0044407 10-Deacetyltaxol B 789.34
BXGC0045260 Taxol C 847.38
BXGC0045289 10-Deacetyltaxayunnanine A 805.37
BXGC0045484 5,7-dihydroxy-3,6-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one 404.11
BXGC0047749 Podoverine A 384.12
BXGC0049133 3-Desmethylcolchicin 385.15
BXGC0049213 Cephalomannine 831.35
BXGC0050385 3-Hydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-5,6,7-Trimethoxychromen-4-One 374.1
BXGC0051028 n.a 434.12
BXGC0051114 Desoxypodophyllotoxin 398.14
BXGC0051401 5,7,3'-Trihydroxy-3,4'-Dimethoxyflavone 330.07
BXGC0051425 Combretastatin A-1 332.13
BXGC0052973 3,5-Dihydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-6,7-Dimethoxychromen-4-One 360.08
BXGC0053369 Centaureidin 360.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein