Showing entry for Lysosome membrane protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013440
Protein NameLysosome membrane protein 2
Uniport IdQ14108
GeneSCARB2
Gene Id950
DomainCD36
Pfam PF01130  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04142 Lysosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015917 aminophospholipid transport
Biological Process GO:0061024 membrane organization
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0006622 protein targeting to lysosome
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0043471 regulation of cellular carbohydrate catabolic process
Biological Process GO:1904978 regulation of endosome organization
Biological Process GO:1905123 regulation of glucosylceramidase activity
Biological Process GO:1905671 regulation of lysosome organization
molecular function GO:0038024 cargo receptor activity
molecular function GO:0051087 chaperone binding
molecular function GO:0015485 cholesterol binding
molecular function GO:0019899 enzyme binding
molecular function GO:0031210 phosphatidylcholine binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0005044 scavenger receptor activity
molecular function GO:0004888 transmembrane signaling receptor activity
molecular function GO:0001618 virus receptor activity
cellular component GO:0030665 clathrin-coated vesicle membrane
cellular component GO:0030666 endocytic vesicle membrane
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0010008 endosome membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0031902 late endosome membrane
cellular component GO:0043202 lysosomal lumen
cellular component GO:0005765 lysosomal membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002986 BXGD000165 Fabry Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003962 BXGD000244 Ascites Pathological Conditions, Signs and Symptoms
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007959 BXGD000507 Charcot-Marie-Tooth Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014378 BXGD000912 Enterovirus Infections Infections
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014550 BXGD000930 Myoclonic Epilepsy Nervous System Diseases
C0016663 BXGD001071 Pathological fracture Wounds and Injuries
C0017205 BXGD001105 Gaucher Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017565 BXGD001118 Gingival Hemorrhage Pathological Conditions, Signs and Symptoms; Stomatognathic Diseases
C0017668 BXGD001143 Focal glomerulosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0018572 BXGD001206 Hand, Foot and Mouth Disease Infections
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020514 BXGD001414 Hyperprolactinemia Nervous System Diseases; Endocrine System Diseases
C0020532 BXGD001420 Hypersplenism Hemic and Lymphatic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022797 BXGD001586 Adult Neuronal Ceroid Lipofuscinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027543 BXGD001997 Avascular necrosis of bone Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029464 BXGD002161 Osteosclerosis Musculoskeletal Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031039 BXGD002274 Pericardial effusion Cardiovascular Diseases
C0033687 BXGD002415 Proteinuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085660 BXGD003228 Aseptic necrosis Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0151669 BXGD003457 Increased antibody level in blood
C0151825 BXGD003481 Bone pain Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0152025 BXGD003521 Polyneuropathy Nervous System Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0234376 BXGD004659 Action Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234378 BXGD004661 Static Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234533 BXGD004687 Generalized seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0262431 BXGD005242 Compression fracture of vertebral column Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Wounds and Injuries
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270922 BXGD006134 Peripheral demyelinating neuropathy Immune System Diseases; Nervous System Diseases
C0349506 BXGD007912 Photosensitivity of skin Skin and Connective Tissue Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376532 BXGD008000 Epilepsy, Rolandic Nervous System Diseases
C0400979 BXGD008268 Obstruction of biliary tree Digestive System Diseases
C0423798 BXGD008510 Increased tendency to bruise Wounds and Injuries
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0541764 BXGD009259 Delayed bone age
C0574002 BXGD009497 Edema of foot (finding) Pathological Conditions, Signs and Symptoms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0740279 BXGD009973 Cerebellar atrophy
C0750937 BXGD010259 Ataxia, Appendicular Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751354 BXGD010404 Myoclonus, Action Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751772 BXGD010583 REM Sleep Behavior Disorder Nervous System Diseases; Mental Disorders
C0751778 BXGD010587 Myoclonic Epilepsies, Progressive Nervous System Diseases
C0751779 BXGD010588 Action Myoclonus-Renal Failure Syndrome Nervous System Diseases
C0751785 BXGD010594 Unverricht-Lundborg Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751837 BXGD010604 Gait Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C1305855 BXGD012348 Body mass index
C1305904 BXGD012349 Familial hematuria
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1838681 BXGD014337 Rapidly progressive
C1847164 BXGD014854 Morning myoclonic jerks Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1961835 BXGD016676 Gaucher Disease, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1963077 BXGD016680 Bone Pain, CTCAE 3.0
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3853962 BXGD019823 Enterovirus 71 infection Infections
C3887513 BXGD019887 Avascular necrosis Pathological Conditions, Signs and Symptoms
C4021757 BXGD020760 EEG with polyspike wave complexes
C4025758 BXGD021779 Abnormal myocardium morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4317123 BXGD022727 Myoclonic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4521256 BXGD023058 Glomerulopathy Assessment
C4553018 BXGD023532 Avascular Necrosis, CTCAE
C4554063 BXGD023559 Bone Pain, CTCAE 5.0
C4721411 BXGD023735 Osteolysis Musculoskeletal Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0038316 Cholesterol 386.35
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein