Showing entry for Protein-tyrosine kinase 2-beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013459
Protein NameProtein-tyrosine kinase 2-beta
Uniport IdQ14289
GenePTK2B
Gene Id2185
DomainFERM_M; FERM_N_2; Focal_AT; Pkinase_Tyr
Pfam PF00373   PF18038   PF03623   PF07714  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
5. Organismal Systems 5.1 Immune system hsa04650 Natural killer cell mediated cytotoxicity
5. Organismal Systems 5.1 Immune system hsa04670 Leukocyte transendothelial migration
5. Organismal Systems 5.2 Endocrine system hsa04912 GnRH signaling pathway
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05161 Hepatitis B
6. Human Diseases 6.9 Infectious diseases: Viral hsa05163 Human cytomegalovirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0042976 activation of Janus kinase activity
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0001525 angiogenesis
Biological Process GO:0006915 apoptotic process
Biological Process GO:0043534 blood vessel endothelial cell migration
Biological Process GO:0045453 bone resorption
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0006968 cellular defense response
Biological Process GO:0071498 cellular response to fluid shear stress
Biological Process GO:0071300 cellular response to retinoic acid
Biological Process GO:0070098 chemokine-mediated signaling pathway
Biological Process GO:0086100 endothelin receptor signaling pathway
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0048041 focal adhesion assembly
Biological Process GO:0014009 glial cell proliferation
Biological Process GO:0045087 innate immune response
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0038110 interleukin-2-mediated signaling pathway
Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway
Biological Process GO:0060292 long-term synaptic depression
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0002315 marginal zone B cell differentiation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0030502 negative regulation of bone mineralization
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010656 negative regulation of muscle cell apoptotic process
Biological Process GO:0045638 negative regulation of myeloid cell differentiation
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0043267 negative regulation of potassium ion transport
Biological Process GO:0031175 neuron projection development
Biological Process GO:0001556 oocyte maturation
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0030838 positive regulation of actin filament polymerization
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:2000538 positive regulation of B cell chemotaxis
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0001954 positive regulation of cell-matrix adhesion
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:2000573 positive regulation of DNA biosynthetic process
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0043507 positive regulation of JUN kinase activity
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0051000 positive regulation of nitric-oxide synthase activity
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
Biological Process GO:0045860 positive regulation of protein kinase activity
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0045727 positive regulation of translation
Biological Process GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:2000249 regulation of actin cytoskeleton reorganization
Biological Process GO:0050848 regulation of calcium-mediated signaling
Biological Process GO:0030155 regulation of cell adhesion
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0010752 regulation of cGMP-mediated signaling
Biological Process GO:2000114 regulation of establishment of cell polarity
Biological Process GO:0032960 regulation of inositol trisphosphate biosynthetic process
Biological Process GO:0010758 regulation of macrophage chemotaxis
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0051279 regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:2000058 regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0051591 response to cAMP
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0009749 response to glucose
Biological Process GO:0009725 response to hormone
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0035902 response to immobilization stress
Biological Process GO:0010226 response to lithium ion
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0006970 response to osmotic stress
Biological Process GO:0007172 signal complex assembly
Biological Process GO:0007165 signal transduction
Biological Process GO:0002040 sprouting angiogenesis
Biological Process GO:0043149 stress fiber assembly
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0033209 tumor necrosis factor-mediated signaling pathway
Biological Process GO:0048010 vascular endothelial growth factor receptor signaling pathway
molecular function GO:0043423 3-phosphoinositide-dependent protein kinase binding
molecular function GO:0005524 ATP binding
molecular function GO:0004683 calmodulin-dependent protein kinase activity
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0031625 ubiquitin protein ligase binding
cellular component GO:0097440 apical dendrite
cellular component GO:0044297 cell body
cellular component GO:0005938 cell cortex
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0005925 focal adhesion
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0030426 growth cone
cellular component GO:0030027 lamellipodium
cellular component GO:0045121 membrane raft
cellular component GO:0043025 neuronal cell body
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0014069 postsynaptic density
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1500931 Cell-Cell communication
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-194138 Signaling by VEGF
R-HSA-391160 Signal regulatory protein family interactions
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-449147 Signaling by Interleukins
R-HSA-451927 Interleukin-2 family signaling
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9020558 Interleukin-2 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008354 BXGD000533 Cholera Infections
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011875 BXGD000757 Diabetic Angiopathies Endocrine System Diseases; Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015674 BXGD001012 Chronic Fatigue Syndrome Infections; Musculoskeletal Diseases; Nervous System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017924 BXGD001155 Glycogen Storage Disease Type V Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0018553 BXGD001203 Hamartoma Syndrome, Multiple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019270 BXGD001311 Hernia Pathological Conditions, Signs and Symptoms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021818 BXGD001514 Intervertebral Disk Displacement Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0022638 BXGD001567 Ketosis Nutritional and Metabolic Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023479 BXGD001663 Acute myelomonocytic leukemia Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023508 BXGD001675 White Blood Cell Count procedure
C0023524 BXGD001681 Leukoencephalopathy, Progressive Multifocal Infections; Nervous System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025319 BXGD001862 Menopausal syndrome Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027962 BXGD002064 Melanocytic nevus Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029458 BXGD002158 Osteoporosis, Postmenopausal Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030499 BXGD002232 Parasitic Diseases Infections
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036205 BXGD002583 Sarcoidosis, Pulmonary Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039263 BXGD002805 Takayasu Arteritis Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042075 BXGD002955 Urologic Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0080032 BXGD003105 Pleural Effusion, Malignant Neoplasms; Respiratory Tract Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0149721 BXGD003349 Left Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200638 BXGD004043 Eosinophil count procedure
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206647 BXGD004212 Dermatofibrosarcoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0242362 BXGD005155 Disk, Herniated Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0243066 BXGD005213 Atresia
C0263874 BXGD005352 Degeneration of lumbar intervertebral disc Musculoskeletal Diseases
C0265808 BXGD005578 Cyanotic congenital heart disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Respiratory Tract Diseases; Cardiovascular Diseases
C0270823 BXGD006112 Petit mal status Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0271680 BXGD006232 Diabetic Polyneuropathies Nervous System Diseases; Endocrine System Diseases
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278787 BXGD006586 Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive Neoplasms; Hemic and Lymphatic Diseases
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279068 BXGD006624 Childhood Solid Neoplasm
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280099 BXGD006712 Adult Solid Neoplasm
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281899 BXGD006788 Prolapsed lumbar disc Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0311335 BXGD006877 Grand Mal Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0341742 BXGD007420 Acute retention of urine Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349782 BXGD007954 Ischemic cardiomyopathy Cardiovascular Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0392784 BXGD008069 Dermatofibrosarcoma Protuberans Neoplasms
C0393734 BXGD008131 Complex Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409952 BXGD008399 Idiopathic osteoarthritis Musculoskeletal Diseases
C0424139 BXGD008520 Anxiety and fear
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0432283 BXGD008764 Osteoglophonic dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553694 BXGD009409 Oropharyngeal disorders Digestive System Diseases; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751522 BXGD010488 Status Epilepticus, Subclinical Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751523 BXGD010489 Non-Convulsive Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751524 BXGD010490 Simple Partial Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948379 BXGD011533 Impaired insulin secretion
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1135868 BXGD011700 Gestational Trophoblastic Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1279296 BXGD012118 Chronic leukemia (category) Pathological Conditions, Signs and Symptoms; Neoplasms
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1321422 BXGD012431 Monoblastic leukemia
C1321865 BXGD012443 Juvenile astrocytoma Neoplasms
C1321872 BXGD012446 Stage IV Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332182 BXGD012495 Adult Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332183 BXGD012496 Adult Astrocytic Tumor Neoplasms
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332309 BXGD012521 Anti-Basement Membrane Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332942 BXGD012558 Childhood Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384584 BXGD012943 Generalized osteoarthritis Musculoskeletal Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1511934 BXGD013184 Differentiating Neuroblastoma Neoplasms
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1512709 BXGD013194 Chronic Lymphoproliferative Disorder of NK-Cells Pathological Conditions, Signs and Symptoms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1562113 BXGD013372 Fleck corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1739135 BXGD013733 Progression of prostate cancer
C1739363 BXGD013734 Prostatic Hypertrophy Male Urogenital Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832976 BXGD013890 Cone-Rod Dystrophy 5 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1842937 BXGD014546 AURAL ATRESIA, CONGENITAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1859592 BXGD015912 ATRICHIA WITH PAPULAR LESIONS Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1867326 BXGD016447 RETINAL CONE DYSTROPHY 1 Eye Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1955860 BXGD016610 Leukemia, Natural Killer Cell Large Granular Lymphocytic Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2004493 BXGD016875 Leukemia, B-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2748055 BXGD017583 Hypoinsulinaemia (disorder)
C2931618 BXGD018040 Gestational trophoblastic disease Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936380 BXGD018112 Neointima Pathological Conditions, Signs and Symptoms
C2937421 BXGD018162 Prostatic Hyperplasia Male Urogenital Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2938983 BXGD018170 Focal cortical dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3160889 BXGD018491 Node-negative breast cancer
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3544205 BXGD019109 Ovarian clear cell carcinoma
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3693482 BXGD019337 Giant Cell Fibroblastoma Neoplasms
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3873567 BXGD019863 Peripheral neuropathy due to and following chemotherapy Nervous System Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887551 BXGD019898 Memory dysfunction Mental Disorders
C3887938 BXGD019929 Deuteranomaly Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4529962 BXGD023178 Fatty Liver Disease
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733093 BXGD023908 progesterone receptor-negative breast cancer
C4733094 BXGD023909 progesterone receptor-positive breast cancer
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
BXGC0005624 Genistein 270.24
BXGC0012352 Chelerythrine 348.12
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein