Showing entry for Splicing factor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013586
Protein NameSplicing factor 1
Uniport IdQ15637
GeneSF1
Gene Id7536
DomainKH_1; SF1-HH; zf-CCHC
Pfam PF00013   PF16275   PF00098  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0033327 Leydig cell differentiation
Biological Process GO:0030238 male sex determination
Biological Process GO:0000389 mRNA 3'-splice site recognition
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:0030575 nuclear body organization
Biological Process GO:0000381 regulation of alternative mRNA splicing, via spliceosome
Biological Process GO:0050810 regulation of steroid biosynthetic process
Biological Process GO:0000245 spliceosomal complex assembly
molecular function GO:0042802 identical protein binding
molecular function GO:0003729 mRNA binding
molecular function GO:0045131 pre-mRNA branch point binding
molecular function GO:0003723 RNA binding
molecular function GO:0003714 transcription corepressor activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005840 ribosome
cellular component GO:0005681 spliceosomal complex
Reactome
Pathway Id Pathway Name
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72172 mRNA Splicing
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0022116 BXGD001531 Ischemia Pathological Conditions, Signs and Symptoms
C0025202 BXGD001832 melanoma Neoplasms
C0025267 BXGD001845 Multiple Endocrine Neoplasia Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Endocrine System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029443 BXGD002152 Osteomyelitis Infections; Musculoskeletal Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0405580 BXGD008325 Adrenal cortical hypofunction Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0949595 BXGD011580 Gonadal Dysgenesis, 46,XX Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2751824 BXGD017742 46, XY Disorders of Sex Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein