Showing entry for Leukotriene B4 receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013590
Protein NameLeukotriene B4 receptor 1
Uniport IdQ15722
GeneLTB4R
Gene Id1241
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006955 immune response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0006936 muscle contraction
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
molecular function GO:0008528 G protein-coupled peptide receptor activity
molecular function GO:0001632 leukotriene B4 receptor activity
molecular function GO:0004974 leukotriene receptor activity
molecular function GO:0000166 nucleotide binding
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-388396 GPCR downstream signalling
R-HSA-391903 Eicosanoid ligand-binding receptors
R-HSA-391906 Leukotriene receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000833 BXGD000014 Abscess Pathological Conditions, Signs and Symptoms; Infections
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004099 BXGD000253 Asthma, Exercise-Induced Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005741 BXGD000328 Blepharitis Eye Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006272 BXGD000385 Bronchiolitis Obliterans Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007273 BXGD000455 Carotid Artery Diseases Nervous System Diseases; Cardiovascular Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0026857 BXGD001943 Musculoskeletal Diseases Musculoskeletal Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027719 BXGD002027 Nephrosclerosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0040921 BXGD002888 Trichomonas Infections Infections
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0086565 BXGD003295 Liver Dysfunction Digestive System Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0221292 BXGD004440 Basophilic leukemia Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0275518 BXGD006375 Acute infectious disease Pathological Conditions, Signs and Symptoms; Infections
C0340629 BXGD007354 Aortic aneurysm without mention of rupture NOS Cardiovascular Diseases
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1519689 BXGD013245 Tumor Promotion Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1960048 BXGD016652 Severe persistent asthma Respiratory Tract Diseases; Immune System Diseases
C1962942 BXGD016677 TRICHOMONAS VAGINALIS (finding)
C2363741 BXGD017100 HIV-1 infection
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3662483 BXGD019270 Allergic sensitization
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein