Showing entry for Syntaxin-binding protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013605
Protein NameSyntaxin-binding protein 2
Uniport IdQ15833
GeneSTXBP2
Gene Id6813
DomainSec1
Pfam PF00995  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0001909 leukocyte mediated cytotoxicity
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0002576 platelet degranulation
Biological Process GO:0043304 regulation of mast cell degranulation
Biological Process GO:0006904 vesicle docking involved in exocytosis
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0017075 syntaxin-1 binding
molecular function GO:0030348 syntaxin-3 binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0016324 apical plasma membrane
cellular component GO:0042582 azurophil granule
cellular component GO:0044194 cytolytic granule
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
cellular component GO:0098793 presynapse
cellular component GO:0030141 secretory granule
cellular component GO:0042581 specific granule
cellular component GO:0070820 tertiary granule
cellular component GO:0042589 zymogen granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114608 Platelet degranulation
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-449147 Signaling by Interleukins
R-HSA-449836 Other interleukin signaling
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76005 Response to elevated platelet cytosolic Ca2+
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0024291 BXGD001757 Lymphohistiocytosis, Hemophagocytic Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035021 BXGD002501 Relapsing Fever Infections
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0241013 BXGD005075 Increased serum ferritin
C0241910 BXGD005123 Autoimmune Chronic Hepatitis Digestive System Diseases; Immune System Diseases
C0267556 BXGD005759 Osmotic diarrhea Digestive System Diseases
C0272199 BXGD006322 Familial Hemophagocytic Lymphocytosis Hemic and Lymphatic Diseases
C0341306 BXGD007401 Microvillus inclusion disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0398686 BXGD008215 Primary immune deficiency disorder Immune System Diseases
C0401151 BXGD008274 Chronic diarrhea Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0876991 BXGD011323 Histiocytosis haematophagic
C1096155 BXGD011605 Macrophage Activation Syndrome Immune System Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1611743 BXGD013456 Familial (FPAH)
C2315100 BXGD017021 Pediatric failure to thrive Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Mental Disorders
C2347747 BXGD017040 Adult Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2751293 BXGD017697 HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 5 Hemic and Lymphatic Diseases
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714772 BXGD019433 Recurrent fevers
C3854388 BXGD019830 Hyperferritinaemia Nutritional and Metabolic Diseases
C3887638 BXGD019906 Failure to thrive in infant Pathological Conditions, Signs and Symptoms
C4023012 BXGD021065 Abnormal natural killer cell physiology
C4289792 BXGD022497 Chronic Active EBV Infection of T-and NK-Cell Type, Systemic Form Infections
C4721555 BXGD023755 Autoimmune hepatitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein