Showing entry for Guanylate kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013668
Protein NameGuanylate kinase
Uniport IdQ16774
GeneGUK1
Gene Id2987
DomainGuanylate_kin
Pfam PF00625  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046034 ATP metabolic process
Biological Process GO:0046060 dATP metabolic process
Biological Process GO:0006185 dGDP biosynthetic process
Biological Process GO:0046054 dGMP metabolic process
Biological Process GO:0046711 GDP biosynthetic process
Biological Process GO:0019673 GDP-mannose metabolic process
Biological Process GO:0034436 glycoprotein transport
Biological Process GO:0015949 nucleobase-containing small molecule interconversion
Biological Process GO:0046939 nucleotide phosphorylation
Biological Process GO:0006163 purine nucleotide metabolic process
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0005524 ATP binding
molecular function GO:0004385 guanylate kinase activity
cellular component GO:0005829 cytosol
cellular component GO:0001917 photoreceptor inner segment
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-2161522 Abacavir transport and metabolism
R-HSA-2161541 Abacavir metabolism
R-HSA-499943 Interconversion of nucleotide di- and triphosphates
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0347016 BXGD007846 Secondary malignant neoplasm of spinal cord Neoplasms; Nervous System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0403397 BXGD008277 Steroid-resistant nephrotic syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C3266102 BXGD018597 Steroid resistant nephrotic syndrome of childhood Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0027925 Cpg 363.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein