Showing entry for Cystic fibrosis transmembrane conductance regulator


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013821
Protein NameCystic fibrosis transmembrane conductance regulator
Uniport IdQ1LX78
Genecftr
Gene Id559080
DomainABC_membrane; ABC_tran; CFTR_R
Pfam PF00664   PF00005   PF14396  
OrganismDanio rerio (Zebrafish) (Brachydanio rerio)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015701 bicarbonate transport
Biological Process GO:1904322 cellular response to forskolin
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0035162 embryonic hemopoiesis
Biological Process GO:0008354 germ cell migration
Biological Process GO:0070121 Kupffer's vesicle development
Biological Process GO:0050891 multicellular organismal water homeostasis
Biological Process GO:0031016 pancreas development
Biological Process GO:0090022 regulation of neutrophil chemotaxis
Biological Process GO:0002679 respiratory burst involved in defense response
Biological Process GO:0035377 transepithelial water transport
Biological Process GO:0055085 transmembrane transport
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0015106 bicarbonate transmembrane transporter activity
molecular function GO:0005254 chloride channel activity
molecular function GO:0005260 intracellularly ATP-gated chloride channel activity
molecular function GO:0016853 isomerase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0034707 chloride channel complex
cellular component GO:0005829 cytosol
cellular component GO:0031901 early endosome membrane
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0055038 recycling endosome membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003500 N-Decane 142.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein