Showing entry for 3-hydroxy-3-methylglutaryl-coenzyme A reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013856
Protein Name3-hydroxy-3-methylglutaryl-coenzyme A reductase
Uniport IdQ1W675
GeneHMGCR
Gene Id100144446
DomainHMG-CoA_red; Sterol-sensing
Pfam PF00368   PF12349  
OrganismSus scrofa (Pig)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0015936 coenzyme A metabolic process
Biological Process GO:0008299 isoprenoid biosynthetic process
Biological Process GO:0016126 sterol biosynthetic process
molecular function GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
molecular function GO:0042282 hydroxymethylglutaryl-CoA reductase activity
molecular function GO:0050661 NADP binding
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005778 peroxisomal membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030338 Ganomycin B 344.2
BXGC0043841 Ganoderone A 454.34
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein