Showing entry for Tyrosine-protein kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT014548
Protein NameTyrosine-protein kinase
Uniport IdQ3ZC95
GeneBTK
Gene Id533459
DomainBTK; PH; Pkinase_Tyr; SH2; SH3_1
Pfam PF00779   PF00169   PF07714   PF00017   PF00018  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002344 B cell affinity maturation
Biological Process GO:0048469 cell maturation
Biological Process GO:0098761 cellular response to interleukin-7
Biological Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0030889 negative regulation of B cell proliferation
Biological Process GO:0001818 negative regulation of cytokine production
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0045121 membrane raft
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000140 Phytic acid 660.04
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein