Showing entry for Protein mono-ADP-ribosyltransferase PARP15


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT014634
Protein NameProtein mono-ADP-ribosyltransferase PARP15
Uniport IdQ460N3
GenePARP15
Gene Id165631
DomainMacro; PARP
Pfam PF01661   PF00644  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0140289 protein mono-ADP-ribosylation
Biological Process GO:0070212 protein poly-ADP-ribosylation
molecular function GO:0003950 NAD+ ADP-ribosyltransferase activity
molecular function GO:0070403 NAD+ binding
molecular function GO:1990404 protein ADP-ribosylase activity
molecular function GO:0003714 transcription corepressor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein