Showing entry for Solute carrier family 22 member 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT014891
Protein NameSolute carrier family 22 member 6
Uniport IdQ4U2R8
GeneSLC22A6
Gene Id9356
DomainSugar_tr
Pfam PF00083  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015742 alpha-ketoglutarate transport
Biological Process GO:0015711 organic anion transport
Biological Process GO:0097254 renal tubular secretion
Biological Process GO:0031427 response to methotrexate
Biological Process GO:0043252 sodium-independent organic anion transport
molecular function GO:0015301 anion:anion antiporter activity
molecular function GO:0031404 chloride ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0005452 inorganic anion exchanger activity
molecular function GO:0008514 organic anion transmembrane transporter activity
molecular function GO:0015347 sodium-independent organic anion transmembrane transporter activity
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005901 caveola
cellular component GO:0070062 extracellular exosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-549132 Organic cation/anion/zwitterion transport
R-HSA-561048 Organic anion transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006663 BXGD000403 Calcinosis Nutritional and Metabolic Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028860 BXGD002093 Oculocerebrorenal Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases
C0028960 BXGD002101 Oligospermia Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0202239 BXGD004087 Uric acid measurement (procedure)
C0263628 BXGD005334 Tumoral calcinosis Nutritional and Metabolic Diseases
C0268113 BXGD005818 Familial juvenile gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0521174 BXGD009133 Microcalcification Nutritional and Metabolic Diseases
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000230 Ochratoxin A 403.81
BXGC0000528 Salicylic acid 138.12
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000663 Papain 206.28
BXGC0000968 Glutaric acid 132.11
BXGC0001273 Hippuric acid 179.17
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0002468 Octanoic acid 144.21
BXGC0002485 2-Oxopentanedioic acid 146.1
BXGC0004709 N-(2-Hydroxybenzoyl)glycine 195.17
BXGC0006193 Ellagic acid 302.19
BXGC0008062 Uric acid 168.11
BXGC0026845 2,4-Dichlorophenoxyacetic Acid 219.97
BXGC0032290 Anandamide 347.28
BXGC0034941 Combretastatin A4 316.13
BXGC0044810 Lamivudine 229.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein