Showing entry for Kelch-like protein 12


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT015011
Protein NameKelch-like protein 12
Uniport IdQ53G59
GeneKLHL12
Gene Id59349
DomainBACK; BTB; Kelch_1
Pfam PF07707   PF00651   PF01344  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048208 COPII vesicle coating
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0014032 neural crest cell development
Biological Process GO:0014029 neural crest formation
Biological Process GO:0006513 protein monoubiquitination
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0042802 identical protein binding
cellular component GO:0034451 centriolar satellite
cellular component GO:0030134 COPII-coated ER to Golgi transport vesicle
cellular component GO:0030127 COPII vesicle coat
cellular component GO:0031463 Cul3-RING ubiquitin ligase complex
cellular component GO:0005829 cytosol
cellular component GO:0000139 Golgi membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-4641258 Degradation of DVL
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0014378 BXGD000912 Enterovirus Infections Infections
C0241910 BXGD005123 Autoimmune Chronic Hepatitis Digestive System Diseases; Immune System Diseases
C4721555 BXGD023755 Autoimmune hepatitis Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein